术前双抗治疗辅助机械取栓治疗急性缺血性脑卒中的效果.pdfVIP

2023年4月第30卷第4期 临床医学工程 501. ·论著· （临床研究） 术前双抗治疗辅助机械取栓治疗急性缺血性脑卒中的效果 1* 刘少哲1，于佩² ，余洋1，温昌明 （南阳市中心医院1神经内科脑血管病介人病区，2医学检验科，河南南阳473000) 【摘要】 目的探讨术前双抗治疗辅助机械取栓治疗急性缺血性脑卒中（AIS ）的效果。方法150例AIS患者分为两组各75 例，对照组接受机械取栓治疗，观察组接受术前规律双抗治疗联合机械取栓治疗，比较两组的治疗效果、神经功能、血管开通情 况及预后。结果观察组的总有效率高于对照组，治疗后1d、3d、14d的NIHSS评分均低于对照组，血管开通率及侧支代偿率 均高于对照组，再闭塞率、再出血率及死亡率均低于对照组（P0.05)。结论术前双抗治疗辅助机械取栓治疗AIS 的效果较好， 可促进患者神经功能恢复，提高血管开通率，改善患者预后转归。 【关键词】 双抗治疗；机械取栓；急性缺血性脑卒中；神经功能；预后 中图分类号：R743.3 文献标识码：A doi:10.3969/j.issn.1674-4659.2023.04.0501 ffect of Preoperative Dual Antiplatelet Therapy Assisted Mechanical Thrombectomy in the Treatment of Acute Ischemic Stroke Il LIU Shaozhe, YU Peilin, YU Yang, WEN Changming * ( Cerebrovascular Disease Intervention Ward of Neurology Department, ? Medical Laboratory Department, Nanyang Central Hospital, Nanyang 473000, China; *Corresponding author: WEN Changming, E-mail:) [Abstract] Objective To explore the effect of preoperative dual antiplatelet therapy assisted mechanical thrombectomy in the treatment of acute ischemic stroke (AIS). Methods 150 cases of AIS patients were divided into two groups, with 75 cases in each group. The control group received mechanical thrombectomy, and the observation group received preoperative regular dual antiplatelet therapy combined with mechanical thrombectomy. The therapeutic effect, neurological function, vascular patency and prognosis were compared between the two groups. Results The total effective rate of the observation group was higher than that of the control group,