NSC632839-Standard-生命科学试剂-MCE.pdfVIP

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NSC632839(Standard)

Cat.No.:HY-100708R

CASNo.:157654-67-6

分⼦式:C₂₁H₂₂ClNO

分⼦量:339.86

作⽤靶点:Deubiquitinase;ReferenceStandards

作⽤通路:CellCycle/DNADamage;Others

储存⽅式:Pleasestoretheproductundertherecommendedconditionsin

theCertificateofAnalysis.

BIOLOGICALACTIVITY

⽣物活性NSC632839(Standard)是NSC632839(HY-100708)的分析标准品。本产品⽤于研究及分析应⽤。NSC632839

是⼀种⾮选择性肽酶抑制剂，抑制USP2，USP7和SENP2，EC50分别为45±4μM，37±1μM和9.8±1.8

μM。

IC50TargetEC50:45±4μM(USP2),37±1μM(USP7),9.8±1.8μM(SENP2)[1]

REFERENCES

[1].NicholsonB,etal.Characterizationofubiquitinandubiquitin-like-proteinisopeptidaseactivities.ProteinSci.2008Jun;17(6):1035-43.

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Caution:Producthasnotbeenfullyvalidatedformedicalapplications.

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1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师