修复霜促进激光／强脉冲光术后皮肤修复的临床观察.pdfVIP

788 中国美容医学 2012年 5月第21卷第5期 ChineseJournalofAestheticMedicine．May．2012．Vo1．21．No．5 · 皮肤美容 · · 论著 · 修复霜促进激光 ／强脉冲光术后皮肤修复的临床观察 徐媛媛，吴 严，耿 龙，高兴华，陈洪铎，李远宏 (中国医科大学附属第一医院皮肤科 辽宁 沈阳 110001) [摘要]目的：观察修复霜对激光及强脉冲光照射处皮肤的修复作用。方法：用Q开关掺钕钇铝石榴石激光、半导体激光、红宝石 激光和强脉冲光依次照射40名健康受试者双前臂屈侧皮肤，分别涂抹修复霜或安慰剂。于照射前、后，肉眼观察局部皮肤反应 ， 用窄谱反射分光光度计检测黑素指数及红斑指数 结果：半导体激光和强脉冲光照射后局部皮肤仅出现轻微红斑，无色素沉着， 除个别时间点外，双侧皮肤黑素指数及红斑指数差别不大；而Q开关掺钕钇铝石榴石激光和红宝石激光照射后，对照侧局部皮 肤出现明显的红斑、轻微的水肿及炎症后色素沉着，治疗侧程度轻于对照侧，且较快消退，于术后 7天及 21天测得黑素指数及 红斑指数均低于对照侧。结论：修复霜有利于减轻激光及强脉冲光术后红斑及色素沉着。 [关键词]修复霜；激光；强脉冲光 [中图分类号]R73O．57 [文献标识码]A [文章编号]1008—6455(2012)05-0788-03 RecoveryCream PromotetheRecovery oftheSkinIrradiatedbyLaserorIntensePulsedLight XUYuan-yuan W UYanIGENG LongIGAOXing—hua CHEN Hong—duo LIYuan—hong (DepartmentofDermatology，TheFirstAffiliatedHospitalofChinaMedicalUniversity，Shenyang110001，Liaoning，China) Abstract：ObjectiveToobservetheeffecfofarecoverycream ontheskinexposedtoIaserandintensepulsedIight (IPL)irradiation．Methods Flexuresofbothforearmsof40volunteersreceivedfourkindsoflightsourceirradiationin succession：Q-switchedNeodymium-dopedYttriumAIumInium Garnet (Nd：YAG)laser，Diodelaser，Rubylaser，and IPL，and recoverycream orplacebocream．Changesoftheskincolorwereobservedusing nakedeyesandmeasured using aMexameterpre—and post-treatments． Results Diode laserand IPL only induced slighterythema and no pigmentationwasobservedonbothsidesThemelanin index and erythemaindexchanged littleinmosttime—·pointsof bothsides．AfterirradiationwithQ—switched Nd：YAG laserand rubylaser，however，obviouserythema，slightlyedema and post—infIammatOry pigmentationwere developed onthecontrolside．Theseresponseswere more seriousand Iasted longerthanthoseonthetreatedside．Fur{hermOre．themelanin indexanderythema indexoftreatedsidewere lowerthanthoseofcontrolside．Conclusions Therecoverycream isprov