非糖尿病急性心肌梗死患者入院时血糖与冠状动脉病变及左心功能的关系.pdfVIP

.. ... .. 【摘要 】 目的 探讨非糖尿病患者入院时血糖与急性心肌梗死(AMI)冠状动脉病变程度及左心功能的关系。 方法 根据入 院时血糖水平将180例经皮冠状动脉介入治疗(PCI)的无糖尿病史的AMI患者分为观察组(85例，血糖≥7．8mm0I／L)和对照组(95 例，血糖7．8mmol／L o对两组的冠脉造影结果及左室射血分数(LVEF)、肌酸激酶(CK)峰值和住院时间进行比较分析。 结果 两组 患者单支血管病变分布的差异无统计学意义(P0．05)，观察组发生多支血管病变的患者明显多于对照组，差异有统计学意义(P0．05 o 观察组CK峰值明显高于对照组，LVEF显著低于对照组，差异均有统计学意义(P0．05或0．01 o 结论 非糖尿病AMI合并入院时 高血糖提示多支血管病变和左心功能减退。 【关键词】 高血糖 心肌梗死 冠状动脉疾病 Association of hyperglycemia on admission with severity of coronary artery disease and left ventricular function in non-diabetic pa- tients with acute myocardial infarction XU Yuansheng．XU Guogen．ZHANG／-lao．Department of Emergency。the Fhst Hangzhou Munici- pal Hospital，Hangzhou 310006，China 【Abstract】 Objective To investigate the association of hyperglycemia on admission with the severity of coronary artery dis— ease and Ieft ventricular function en acute myocardial lnfarction of non—diabetic patients．Methods ORe hundred and eighty non—di— abetic patients with acute myocardial infarction(AMI)treated with PC1 were divided into control group(7．8mmol／I)and observation group(／7．8mmol／I)according tothe blood glucose level on admission．The coronary angiography findings，LVEF，maximum CK and mean time of hospitalization were compared between two groups．Results Patients with hyperglycemia had more prevalence of multivessel coronary disease(尸0．05)，higher maximum CK(P0．05)and lower LVEF(P0．01)than patients without hyperglycemia， lhere were no significant differences in lnfarcfion—rela1ed artery and mean_[ime of hospitalization between two groups． Conclusion Hyperglycemiainnon——diabeticAMIpatientsmaysuggestmultivesselcoronarydiseaseandleftventricularhypofunction 【Key words】 Hyperglycemia Acute myocardial infarction Coronary artery disease 糖尿病已被认为是冠心病的等危症，合并糖尿病的 胸痛时间≥30min；(2)特征性的心电图表现，并有动态 冠心病患者有着更高的发病率和病死率Ⅲ。但对于部分 改变：至少2个肢体导联sT段抬高10．1mV或胸前导 非糖尿病冠心病患者，其发病时也常伴有血糖升高，有 联10．2mV，或普遍