基于开放式非相关文献分析的糖尿病肾病中医诊疗知识发现研究.pdfVIP

·710 · 国际中医中药杂志2011年8月第33卷第8期 Int J Trad Chin Med, August 2011, Vol. 33, No.8 ·信息研究 · 基于开放式非相关文献分析的糖尿病肾病 中医诊疗知识发现研究 高宏杰 赵英凯 崔蒙 赵进喜 【摘要】 目的 探求有效治疗糖尿病肾病（diabetic nephropathy ，DN ）的中医药方法，为科研和 临床工作提供参考。方法 采用开放式非相关文献知识发现法对中医药领域 DN 的相关文献进行分析， 挖掘隐藏在糖尿病肾病非相关文献间的隐秘联系，形成有价值的科学假设，对所获得的假设进行专家论 证，从而引导并实现知识发现。结果 运用基于主题词词频统计的开放式非相关文献知识发现方法研究 后，抗炎药（中药）被筛选出来，且多数具有抗炎作用的中药属于清热解毒、祛风胜湿类。结论 以清 热解毒、祛风胜湿为治法进行组方，可能延缓 DN 的发生、发展。 【关键词】 中医药；糖尿病肾病；非相关文献知识发现 Research on knowledge discovery based on non-interactive literatures analysis of diabetic nephropathy diagnose and therapy * GAO Hong-jie , ZHAO Ying-kai, CUI meng, ZHAO Jin-xi. *China Department of Intelligence Research Institute of Medical Informatics, China Academy of Traditional Chinese Medical Sciences, Beijing 100700 【Abstract 】 Objective To explore more effective treatments of Chinese medicine for diabetic nephropathy . Methods This study took opened non-relevant documents knowledge discovery method to study the diabetic nephropathy literatures in order to find the hidden links among literatures. A valuable scientific hypothesis will be put forward upon the study to guide or implement a new knowledge discovery after it acquire the agreement of experts. Results Use keywords frequency statistics method based on open non-related literature knowledge discovery, the anti-inflammatory herbs were filtered out. Most herbs with anti-inflammatory effects had the functions of clearing away heat and detoxicating, expelling wind and removing dampness. Conclusion Prescriptions with the functions of clearing away heat and detoxicating,