丹红注射液辅助治疗肺心病80例疗效观察.pdfVIP

WORLD CHINESEMEDICINE February．2015，Vo1．10，No．2 丹红注射液辅助治疗肺心病 8O例疗效观察 魏 梅 宋煜勋 周 红 (1首都医科大学电力教学医院，北京，100069；2首都医科大学健康管理中心，北京，100069) 摘要 目的：评价丹红注射液治疗慢性肺源性心脏病临床疗效。方法：慢性肺心病患者 80例随机分为2组，对照组4O例 进行常规治疗，治疗组40例在常规治疗的基础上加用丹红注射液。观察2组患者治疗前后症状体征、肺功能、超声心动 图、血气分析和6分钟步行距离的变化。结果：治疗组在总体疗效有效率、各临床症状体征改善率方面均高于对照组，2组 患者在治疗后其血气分析、肺功能、超声心电图和6分钟步行距离方面均有改善，治疗组改善更明显，具有统计学意义(P 0．05)。结论：丹红注射液可缓解慢性肺源性心脏病的各种临床症状，并有改善肺功能，降低肺动脉压，提高运动耐力。 关键词 丹红注射液；慢性肺源性心脏病；肺功能；血气分析；肺动脉收缩压；6分钟步行距离 ClinicalObservationonTherapeuticEffectofDanhongInjectionTreating80Cases ofPulmonaryHeartDiseaseasAdjuvantTherapy W eiMei，SongYuxun ，ZhouHnag (1DepartmentofRespirationMedicine，ElectricPowerTeachingHospitalofCapitatMedicalUniversity，＆ 100073，China； 2HealthManagementCentre(Song Yuxun)，EelctricPowerTeachingHospitalofCaptialMedicalUniversity， 100073，China) Abstract Objective：ToevaluatetheefficiencyofDanhonginjectioninthetreatmentofpulmonaryheartdisease．Methods：A randomized，positivedrugcontrolledclinicaltrial designwasused．Eightypatientswhowerediagnosedclinicallyaspulmonary heartdiseasewerernadomlydividedintotwogroups．Fortypatientsinthecontrolgroupweretreated’vitllconventional therapy． FortypatientsintreatmentgroupweretreatedwitIlDanhonginjectioncombinedw westernmedicine．Thesymptomsandsigns． pulmonaryfunctions，ultrasoniccardiogram，bloodgasanalysisas wellas changeinsix-minute—walkdistanceofthepatientsbefore andafterthetreatmentwereobserved．Results：Thetotal effectiverateinclinical syndromeintreatmentrgoupWas singificantly higherthna thatinthecontrolgroup(P0．05)．Andotherfactorsintwogroupsofpatientswerecompraed．Theresultsshowed thathtePaq，PaCO2，PASP，FEV1％，FEV1／FVCnad6HWDofobservationgroupwassingificantlyhigherthanthecontrol rgoup(P0．05)．Conclusion：Danhonginjectioncanrelievedifferentsymptomsofchronicpulmonaryheartdiseas