阿司匹林预防缺血性脑卒中复发失败的原因分析.pdfVIP

2007, 13( 5) J o urna l of H ai nan M e di cal C ol le ge 439 ( , 437307) [ ] 目的: 探讨阿司匹林在缺血性脑卒中二级预防中失败的原因方法: 收集2002 年1月~ 2004 年 12 月入住本院的脑梗 患者253 例, 均口服阿司匹林进行二级预防, 跟踪随访并分析年龄性别高血 压糖尿病心脏疾病高血脂及阿司匹林抵抗等对复发率的影响结果: 分析表明, 年龄高血压糖尿 病心脏疾病和高血脂均是缺血性脑卒中复发的危险因素( P 005) , 另外阿司匹林抵抗可能也是导致 复发的重要原因结论: 许多因素都会影响阿司匹林二级预防缺血性脑卒中的效果, 提示在缺血性脑卒 中的二级预防中, 需对这些危险因素进行适当处理 [ ] 阿司匹林; 脑梗塞; 脑血管意外; 复发 [ ] R74333 [ ] A [ ] 2007) Causeanalysisof secondary preventionfailureonbrain ischemicstroke by aspirin GE Beihai ( D ep ar tme nt of I nt ernal M ed ici ne, Ch i bi M unicip al P eop l e s H osp it al , H ubei, Chi bi 437307, P. R . of Chi na ) [ABSTRACT] Objective: T o inve tigate the failur e cau e of a pirin in econdary prevention of brain i chemic troke. ethods: 253 ca e of ho pitalized patient w ith i chemic troke from January 2002 to De cember 2004 w er e follow ed up. For econdary prevention, all the patient w er e admini trated a pirin daily and the recurrence co ndition w ere further inve tigated. Po ible ri k f actor re ulting in recurrence, in cluding age, ex , hyperten ion, diabete , hear t di ea e , hy perlipemia and a pir in re i tance w ere re v iew ed. Results: Data definitely indicated that age, hyper ten ion, diabete , heart di ea e and hyper lipemia w er e the r i k f actor ( P 005) . A pirin re i tance m ight al o play a role in r ecur rence. Conclu sion: The effectivene of a pirin in eco ndary prev ention of i chemic troke i influenced by many factor . The e ri k f actor hould be con idered and treated w hile adm ini tration of a pir in in eco ndary prevention of brain i chemic troke. [KEY WORDS] A pirin; Cer ebral infarctio n; Cerebral accident; Recur rence