临床药师参1例尖端扭转性室性心动过速的药学实践.pdfVIP

临床药师参与 1 例尖端扭转性室性心动过速的药学实践 1 2 1 2 韩 强 ，杜金凤 （徐州医学院附属医院药学部，江苏 徐州 221006 ； 新疆伊犁州奎屯医院，新 疆 伊犁 833200 ） 摘 要 目的 通过临床药师全程参与1例尖端扭转性室性心动过速的药物治疗过程，探讨临床药 师在临床治疗中发挥的作用。方法 作者通过参与1例尖端扭转性室性心动过速的药物治疗，探讨 心血管专业临床药师在临床上可以发挥的作用，为临床药师如何提供药学监护和提高药物治疗疗效 提供参考。结果 临床药师参与临床治疗可以帮助医师用药更规范、合理，提高治疗效果，减少病 死率。结论 本病例可以直接体现出临床药师在临床发挥的作用和参与临床药物治疗的必要性。 关键词 尖端扭转性室性心动过速；药物治疗；临床药师；药学实践 Clinical Pharmacists’ Pharmacy Practice for a Patient with Torsades De Pointes Ventricular Tachycardia Event 1 2 1 HAN Qiang ，DU Jin-feng ( Affiliated Hospital of Xuzhou Medical College of Pharmacy, Jiangsu Xuzhou, 2 221006,China ； Xinjiang Yili Kuitun hospital, Xinjiang Yili, 833200, China) ABSTRACT OBJECTIVE：By clinical pharmacists involved throughout the process of one case of drug treatment torsades de pointes ventricular tachycardia, and to explore the role of clinical pharmacists play in clinical treatment. METHODS ：By participating in one case of torsades de pointes ventricular tachycardia therapy, to investigate the role of clinical pharmacists in cardiovascular clinical professional can play for clinical pharmacists to provide pharmaceutical care and improve the efficacy of drug treatment to provide reference. RESULTS ：The results of clinical pharmacists to participate in clinical drug therapy can help physicians more standardized, reasonable and improve the therapeutic effect and reduce mortality. CONCLUSIONS ：This case can be directly reflect the role played by clinical pharmacists in clinical and necessity of participation in clinical drug treatment. KEYWORDS Torsades De Pointes Ventricular Tachycardia Event; Drug Therapy; Clinical Pharmacist; Pharmaceutical Practice 胺碘酮属于Ⅲ类抗心律失常药，主要电生理效应是延长各部心肌组织的动作电位及 有效不应期，有利于消除折返激动。由于复极过度延长，口服后心电图有 Q-T 间期延 长及T 波改变，可以减慢心率15% ～20%，使PR 和Q-T 间期延长10%。适