糖胃康对糖尿病胃轻瘫大鼠胃肽能神经的影响.pdfVIP

糖胃康对糖尿病胃轻瘫大鼠胃肽能神经的影响 ●肖万泽1 付伟1 陈俊1 张萌1 毕会民2 摘要 目的：探讨中药复方糖胃康对糖尿痛胃轻瘫(简写DGP)大鼠胃肽能神经的影 响。方法：将实验大鼠分为正常对照组、模型对照组、糖胃康大、小剂量组、胃复安组，分别 给药灌胃4周后处死，取胃窦部组织测定并分析其肽能神经面积和光密度。结果：模型组与空 著以改善DGP大鼠的胃肽能神经病变。 ABSTRACT intothe ofa herbal onthe Aim：To probe impactpatent nervesofratswithdiabetic rats gastricpeptidergic weredividedintofive control control Tan— group，modelgroup，large—dose groups，namely，normal and ratswere group．The drip— group，small—doseTangWeiKanggroupMetoclopramide gWeiKang fedwithrelevantforfourweeks andthen werekilledandtissuefrom antrum drugs running they gastric and the andareaofVIPaswellasCGRP．Re— ofeachratwastakentomeasure analyzeopticaldensity andareaofbothVIPandCGRPofmodel were lowerthan suhs：The dramatically opticaldensity group four—weektreatmentwith thoseofblankcontrol TangWeiKang，theoptical group(P0．叭)．After of orsmall——dose werebothevi·- andareaofVIPandCGRP density large——dose TangWeiKanggroup in withthoseofmodel 1 or theoutcomeof dentlyhighercomparison group(P0．0P0．05)while remainedthesamein traditionalChinese Metoclopramidegroup ofDGP—afflictedrats． can neurop