体力活动与乳腺癌患者预后关系的Meta分析.pdfVIP

of Science2015 V01．30No．2 · · JournalNursing Jan． 94 ·文献分析· 体力活动与乳腺癌患者预后关系的Meta分析 戚倩1，吴蓓雯2，赵俊杰2，方琼3，朱唯一2 摘要：目的评价体力活动与乳腺癌患者预后的关系。方法计算机检索Cochrane 患者预后的队列研究、病例对照研究，同时筛检纳入文献的参考文献。由2名研究者对文献质量进行评鉴，对纳入研究使用Rev Man5．O进行Meta分析。结果纳入9篇文献，均为队列研究，共计25163例乳腺癌患者。Meta分析显示，乳腺癌确诊前进行体 o．01]，而阴性者未发现具有统计学意义。结论体力活动尤其是确诊后体力活动对乳腺癌患者预后生存具有保护作用，且对雌激 素受体阳性乳腺癌作用明显，无论BMI高低均受益。 关键词：乳腺癌； 体力活动；锻炼；预后； 死亡率； Meta分析 文献标识码：A 文章编号：1001—4152(2015)02一0094一06 中图分类号：R473．73；R737．9 andsurvivaIafterbre躯tcancer meta Physicalactivity diagn∞is：aanaIysis∥QiQ妇押，w“B已i训P以，Z^no-，“起JiP，F彻gQong，Z^“ 200D25，(Mi门n) Ⅵ0iyi∥(Sf^oozo，N“rsi对g，S^血订g^ni．，i口o￡ongLhi伽rsify，s^以九g^口i Toevaluatethe between levelandbreastcanceroutcomeswomenwitha Abstract：objective relationshipphysicalactivity among historvofbreastcancer．MethodsAnelectronicsearchofCochraneLibrary，websiteoftheAmerican andcasecontr01studiesthat the Scholar，CBM，CNKIand was Thecohortstudies RAN0，Google Wanfangcompleted． reported between andoutcomesofbreastcancerwereincluded．Tworesearchers extracteddata associationphysicalactivity independently andassessed theincludedstudieswere withthe 5．O． ResuItsNinecohortstudies studyquality，then analyzed ReviewⅣIanager 25163 mettheinclusioncriteriaandwereincludedinthe foundthat includingpatients meta—analysis．Ouranalysis physicalactivity a11 the hazard before decreasedthe causes diagnosis mortallty，withpooled ration(PHR)being whereastheeffectonreductionofbreastcancerde