《S-(2-乙酰苯基)-二甲基硫代氨基甲酸酯环合产物的确定》.pdfVIP

有机化学 Journalof NOTE Chinese OrganicChemistry S-(2一乙酰苯基)一二甲基硫代氨基甲酸酯环合产物的确定 戈 俊口 裘 亚口 王春丽以 Jesse 陈 瑛榔 Yan96 (“复旦大学药学院上海201203) Internfrom M．Gunn (6 Henry HighSchool，PaloAlto，CAUSA) 摘要通过1H 产物为苯并一2H-噻哺一2一酮，而非文献报道的苯并一4日一噻哺一4一酮．探讨了苯并一2H-噻喃一2一酮和苯并一4缮噻喃．4。酮结构在 氢谱上的规律性差异． 关键词 苯并一4肛噻喃一4．酮；苯并一2H-噻喃一2一酮；环合；S-(2一乙酰苯基)一_-Z甲基硫代氨基甲酸酯 on of ClarificationtheStructureof Product Cyclization Dimethylthiocarbamate S-2一AcetyIphenyl Ge，Jun4Qiu，YaWang，Chunli。Yang，Jesse6Chen，Ying：l：，4 ofMedicinalChemtry，SchoolofPharmacy，FudanUniversity，Shanghai，China) (“Department M．GunnSchool，PaloAlto，CA (6InternfromHenry High USA) from of withNaHin AbstractThestructureof thereaction cyclizationproduct S-2一acetylphenyldimethylthiocarbamate was 1H and tobea insteadofabenzo一4皿 DMFclarified NMR．NOE by X．ray．Itproved benzo．2H-thiopyran一2一one inliterature．TheHMNRchemicalshiftdataofscven andbenzo．4胁 thiopyran一4一onereported benzo．2H-thiopyran．2．ones were be for frombenzo一4厚 discussed．whichuseful thiopyran一4一ones might distinguishingbenzo一2H-thiopyran-2-ones thiopyran-4-ones． Keywords Suksdorfin(1)是从植物Lomatium Suksdorfii[1】的果 实中分离得到的一种天然产物，对其进行结构