老年贫血合并脑梗死患者的临床相关危险因素分析.docVIP

老年贫血合并脑梗死患者的临床相关危险因素分析 　　【摘要】 目的：分析老年贫血患者合并脑梗死的发病机制和危险因素。方法：选取380例神经内科及老年科治疗的≥60周岁的老年脑梗死患者为研究对象，根据入院时血红蛋白结果分为贫血性脑梗死组113例和非贫血性脑梗死组267例，对患者的病史、入院情况及相关检查等13个因素进行单因素分析，并将有意义的单因素进行多因素Logistic回归分析。结果：对贫血性脑梗死与非贫血性脑梗死患者中可能相关的13个因素进行比较，发现年龄、性别、NIHSS评分、冠心病病史、慢性肾衰竭、出血性脑血管病病史、吸烟及饮酒组间比较差异有统计学意义（P0.05）；将有意义的单因素纳入多因素回归分析，提示年龄（OR 1.03；95%CI 1.01-1.05）、慢性肾衰竭（OR 1.42；95%CI 1.03-1.92）及出血性脑血管病病史（OR 3.42；95%CI 1.18-9.43）是老年贫血合并脑梗死的独立危险因素。结论：与非贫血性脑梗死相比，年龄、慢性肾衰竭及出血性脑血管病病史为老年贫血合并脑梗死的独立危险因素。 　　【关键词】 脑梗死； 贫血； 老年； 危险因素 　　【Abstract】 Objective：To analyze the pathogenesis and risk factors of cerebral infarction in elderly patients with anemia Method：380 elderly patients with anemia combined with cerebral infarction were selected as the research object， according to the result of hemoglobin on admission， they were divided into the anemia cerebral infarction group （113 cases） and non anemia cerebral infarction group （267 cases）， the history and the relevant examination 13 factors such as the single factor analysis， and place the meaningful single factor in the multi-factor Logistic regression analysis.Result：13 risk factors were compared among the anemia group in patients with cerebral infarction and nor anemia group， and we found that age， gender， NIHSS score， history of coronary heart disease， chronic renal failure， hemorrhagic cerebrovascular disease history， smoking and drinking difference between groups were statistically significant （P0.05）. Compared with the control group， age （OR 1.03； 95%CI 1.01-1.05）， chronic renal failure （OR 1.42； 95%CI 1.03-1.92） and hemorrhagic cerebrovascular disease history （OR 3.42； 95%CI 1.18-9.43） is independent risk factors for cerebral infarction.Conclusion：Compared with non anemia cerebral infarction group， age， history of chronic renal failure and hemorrhagic cerebrovascular disease were the independent risk factors for cerebral infarction. 　　【Key words】 Cerebral infarction； Anemia； Old； Risk factors 　　First-author’s address：Liaoning Province Jinqiu