舒芬太尼复合咪唑安定辅助椎管内麻醉临床效果研究.docVIP

舒芬太尼复合咪唑安定辅助椎管内麻醉临床效果研究 　　【摘要】 目的：探讨舒芬太尼复合咪唑安定辅助椎管内麻醉的临床效果和应用价值。方法：选择90例择期开腹手术的患者行椎管内麻醉，随机数字表法分两组，每组45例，Ⅰ组为舒芬太尼联合咪唑安定，Ⅱ组为芬太尼联合咪唑安定，比较临床效果。结果：在麻醉诱导后、手术开始、结束时Ⅰ组患者的收缩压、舒张压均明显低于Ⅱ组，比较差异有统计学意义（P0.05）；Ⅰ组对心率与用药前相比的影响比Ⅱ组大，腹腔进行冲洗和探查时，Ⅰ组有体动反应的出现，且心血管波动幅度不如Ⅱ组明显。SpO2 Ⅰ组的相关参数略高于Ⅱ组，且诱导中出现SpO293%的患者例数Ⅱ组多于Ⅰ组。结论：作为椎管内麻醉的辅助用药，舒芬太尼复合咪唑安定镇静镇痛和顺行性遗忘作用效果好，起效快，安全且不良反应发生率小。 　　【关键词】 舒芬太尼； 咪唑安定； 椎管内麻醉 　　Observation on the Clinical Effect of Sufentanil and Midazolam Intraspinal Anesthesia/ZHAO Qing-mei.//Medical Innovation of China，2015，12（10）：029-031 　　【Abstract】 Objective： To investigate the effect of sufentanil midazolam intraspinal anesthesia clinical effect and application value. Method： In our hospital 90 elective abdominal operation patients with intraspinal anesthesia， were randomly divided into two groups， 45 cases in each group， Ⅰ group sufentanil combined with midazolam， Ⅱ group and fentanyl combined with midazolam， analyze clinical effect of the two groups. Result： After induction of anesthesia， operation began， at the end of Ⅰ group patients with systolic blood pressure， diastolic blood pressure were significantly lower than that of the Ⅱ group， the difference was statistically significant （P0.05）. Analgesic and sedative effect of the Ⅰ group than that of the Ⅱ group， the Ⅱ group to maintain the dosage was small， the onset time of the Ⅰ group than in the Ⅱ group quickly， adverse reaction and inhibition of respiratory complications were less than the Ⅱ group， in the wash and exploration on the abdominal cavity， Ⅰ group had the body movement， and cardiovascular fluctuations than the Ⅱ group was significantly. Conclusion： As adjuvant of spinal anesthesia， the composite sufentanil midazolam sedation and anterograde amnesia effect is good， fast， safe and adverse reaction rate. 　　【Key words】 Sufentanil； Midazolam； Spinal anesthesia 　　First-author’s address： Shanxi Province Datong Tianzhen County Maternal and Child Baojian Railway Station， Tianzhen 038200， China 　　doi：10.3969/