艾司洛尔联合胺碘酮治疗心室电风暴160例临床分析.docVIP

艾司洛尔联合胺碘酮治疗心室电风暴160例临床分析 　　[摘要] 目的 探讨和分析盐酸艾司洛尔与胺碘酮联合使用在治疗心室电风暴患者的效果。方法 整群选取该院在2011年9月―2014年6月期间所收治的329例心室电风暴患者，遵照随机与知情自愿原则，分为观察组（160例）和对照组（169例）。给予药物胺碘酮治疗，对观察组患者采用盐酸艾司洛尔与胺碘酮联合治疗方案，疗程结束后，认真观察和对比两组患者所取得治疗的效果。结果 观察组患者总有效率为95.0%，明显高于对照组的70.4%，该两组患者总有效率对比，差异有统计学意义（P 0.01）；治疗后观察组患者收缩压与心率分别为（104.0±15.0）mmHg、（84.0±13.0）次/min全部低于对照组，该两组患者治疗后的收缩压与心率对比，差异有统计学意义（P 0.05）。 结论 采用盐酸艾司洛尔联合药物胺碘酮共同治疗心室电风暴患者的临床效果满意，能够提高心室风暴患者的治愈率，具有临床推广价值。 　　[关键词] 胺碘酮；艾司洛尔；心室电风暴 　　[中图分类号] R541.7 [文献标识码] A [文章编号] 1674-0742（2015）04（c）-0099-02 　　[Abstract] Objective To explore and analyze the effects of esmolol hydrochloride combined with amiodarone in the treatment of patients with ventricular electrical storm. Methods In our hospital from 2011 September to 2014 June， during the 329 cases of patients with ventricular electrical storm， random and follow the principle of voluntary informed， divided into the observation group （160 cases） and control group （169 cases）. Given the drug amiodarone treatment， the observation group were treated by hydrochloric acid esmolol and amiodarone combination therapy， after the treatment， careful observation and comparison of two groups of patients achieved treatment effect. Results In the observation group， the total effective rate was 95%， significantly higher than the control group of 70.4% patients in the two group， the total efficiency of contrast， with significant difference （P 0.01）， there is statistical significance； after the treatment， the patients in observation group were systolic blood pressure and heart rate were（104±15） mmHg，（84±13） time / min all lower than the control group， compared the systolic pressure and heart rate of the two groups of patients after the treatment， it has obvious difference （P 0.05）， there is statistical significance. Conclusion Using esmolol hydrochloride combined with drug amiodarone better clinical effect of ventricular electrical storm with a common treatment， can improve the life quality of life in patients with ventricul