小儿热性惊厥复发相关因素的临床探析.docVIP

小儿热性惊厥复发相关因素的临床探析 　　doi：10.3969/j.issn.1007-614x.2014.22.43 　　摘要目的：探讨小儿热性惊厥复发的相关因素，为以后临床制定防范措施提供可靠数据。方法：2011-2012年收治热性惊厥复发患儿50例，设为观察组；另选本院同期收治热性惊厥无复发患儿50例，设为对照组。对两组临床资料以回顾性方法进行分析。结果：单因素分析结果显示，影响患儿热性惊厥发热的因素包括首次发作年龄、惊厥次数、体温、脑电图异常、围生期异常以及家族癫痫病史；多因素Logistic分析结果显示，相关影响因素有首次发作年龄、体温偏低、生活环境恶劣、家族癫痫病史以及复杂性惊厥等。结论：导致患儿出现热性惊厥复发的因素多种多样，对于存在高危潜在风险因素的热性惊厥患儿需要密切观察，通过合理的方法来避免出现惊厥复发。 　　关键词热性惊厥；小儿；复发；相关因素 　　Clinical study on the relative factors of recurrence of febrile convulsion in children 　　Tian Fashu 　　Department of Pediatrics，the People’s Hospital of Ningling Country，Henan 476700 　　AbstractObjective：To investigate the related factors of the recurrence of febrile convulsion in children，in order to provide reliable data for clinical prevention measures.Methods： 50 cases of recurrence of febrile convulsion in children were selected from 2011 to 2012 as the observation group.We selected the other 50 cases with febrile convulsion but no recurrence in our hospital at the same period as the control group.We retrospective analyzed the clinical datas of them.Results：The single factor analysis showed that the influencing factors in children with febrile convulsion fever included onset age，convulsion times，temperature， abnormal EEG，perinatal abnormalities and family history of epilepsy.Multivariate Logistic regression analysis showed that the related factors included the first age，low body temperature，living environment，family history of epilepsy and the complexity of convulsion.Conclusion：Factors that cause the recurrent of febrile seizures in children are varied.For the existence of the risk of potential risk factors in children with febrile seizure need close observation，to avoid the seizure recurrence by reasonable method. Key wordsFebrile convulsion；Children；Recurrence；Related factors 　　在儿科临床上，惊厥属于较为常见的小儿疾病，而其中又以热性惊厥类型发病率最高，热性惊厥一般好发年龄阶段在3个月～4岁的小儿。有研究显示，小儿出现热性惊厥的概率最高可达到0.5%，且热性惊厥在首次发作后有较高的复发可能性，复发率最高可达到40%。小儿热性惊厥复发的情况会出现各种变化，受到遗传因素还有环境因素的影响较为明显[1]。热性惊厥的高发病和高复发特性决定了它对患儿身体健康和生