基于生物电阻抗法的椎弓根螺钉植入导航系统.docVIP

基于生物电阻抗法的椎弓根螺钉植入导航系统 钟胜河，邓亲恺1，郭劲松1，梁妃学1,王智运2，朱浩1 1. 南方医科大学基础医学院生物信息学重点实验室，广东省广州市 510515 2. 广州军区广州总医院，广东省广州市510515 摘要：介绍一种基于生物电阻抗测量椎弓根螺钉植入手术导航系统。该导航系统由两大部分组成：生物电阻抗测量仪和PC机显示界面。生物电阻抗测量仪设计是基于生物电阻抗法测量原理，根据前期实验成果，刺激频率采用了双频的方法，配合融手术开路器与激励测量功能于一体的双极电极。仪器设计以MSP430F1612微处理器为核心，外围电路则是由直接数字合成芯片AD9850和芯片AD8302组成，并USB将数据发送到个人电脑显示抗实验数据表明：该导航系统能实时、准确地反应插入电极到达骨组织的不同部位，从而可望在临床椎弓根螺钉植入手术中起到导航作用。 关键词：生物电阻抗；椎弓根螺钉植入手术；MSP430F1612；直接数字合成技术 中图分类号： TP391.7 文献标志码：A Researchment of pedicle screw implantation navigation system based on bioelectric-impedance method Chong Shenghe1 ,Yang Jianming1, Guo Jinsong1, Liang Feixue1,Wang Zhiyun2,Zhu Hao1 (1. Institute of Bioinformatics, School of Basic Medical Sciences, Southern Medical University, Guangzhou, 510515, China; 2. Orthopedic Hospital of Guangzhou General Hospital of Guangzhou Military Area, Guangzhou Guangdong 510010, China) Abstract: Introduce a pedicle screw implantation surgery navigation system based on bioelectric-impedance method. The navigation system consists of two parts: the bioelectrical impedance measuring instrument and a PC for display and interaction with doctor. Bioelectric-impedance measuring instrument is designed based on a dual-frequency method according to the results of previous results of our team, the bipolar electrode is built by combining the opening surgery trace device with the stimulator and sensor . MSP430F1612 microprocessor is as the core of instrument design, the peripheral circuits are built by direct digital synthesis chip AD9850 and chip AD8302 , the acquired data is sent data to the PC by USB for real-time display. Navigation system is tested by 6 vertebras of experiment pigs for preliminary verification, the acquired bioelectric-impedance data shows that: the navigation system can accurately reflect the different tissue sit which the inserted electrode reach in real time, so that the system may be play a navigation rule in clinical pedicle screws surgically implanting i