老年髋关节置换患者围手术期急性低血压与术后认知障碍的相关性研究.docVIP

老年髋关节置换患者围手术期急性低血压与术后认知障碍的相关性研究 　　[摘要] 目的 探讨老年髋关节置换患者围手术期急性低血压与术后认知障碍的关系。方法 方便选择2012年1月―2015年12月期间在该院行髋关节置换手术治疗的老年患者96例作为研究对象， 按围手术期是否出现急性低血压分为急性低血压组和正常血压组，并利用简易智能量表（MMSE）对患者的认知功能进行评定。结果 急性低血压组认知功能障碍发生率为39.13%显著高于正常血压组（14.00%），差异有统计学意义P0.05。结论 老年髋关节置换患者围手术期急性低血压可明显增加术后认知功能障碍的发生。 　　[关键词] 老年患者；急性低血压；围手术期；术后认知功能障碍 　　[中图分类号] R816.8 [文献标识码] A [文章编号] 1674-0742（2016）08（c）-0031-03 　　The Relationship between Perioperative Acute Hypotension and Postoperative Cognitive Dysfunction in Elderly Patients with Hip Replacement 　　PANG Jin-ju ， LI Hai-yun 　　Huangdao District of Qingdao City Second Peoples Hospital Bone Second Division， Qingdao，Shandong Province，266400 China 　　[Abstract] Objective Discussed in elderly patients with hip replacement perioperative acute hypotension and the relationship between postoperative cognitive impairment.Methods Convenient selection during the period of January 2012 to December 2015 underwent hip replacement surgery in the treatment of 96 patients were as the research object， according to peri operative period whether acute hypotension is divided into acute hypotension group and normal blood pressure group， and the use of simple intelligent table （MMSE） on the patients cognitive function can were evaluated. Results Acute hypotension group had a significantly higher incidence of cognitive dysfunction was 39.13% normal blood pressure group （14.00%） and significant difference （P 0.05）. Conclusion In elderly patients with hip replacement perioperative acute hypotension may obviously increase the incidence of postoperative cognitive dysfunction. Acute hypotension group had a significantly higher incidence of cognitive dysfunction was 39.13% normal blood pressure group （14.00%） and significant difference （P 0.05）. 　　[Key words] Elderly patients； Acute hypotension； Perioperative period； Postoperative cognitive dysfunction 　　老年患者术后常出现以精神错乱、焦虑、人格改变及记忆受损为表现的中枢神经系统并发症，这种老年患者手术后的认知能力、人格及社交能力和技巧的变化称术后认知功能障碍（POCD）[1-2]。POCD确切的发病机制目前仍不十分清楚[3]。该次研究方便