Eosinophilic gastroenteritis.docVIP

 PAGE \* MERGEFORMAT 16 Eosinophilic gastroenteritis [Keywords:] eosinophilic gastroenteritis, eosinophilia, corticosteroids, literature review Eosinophilic gastroenteritis (eosinophilic gastroenteritis, EG) is a rare benign disease, it layers involving the digestive tract is characterized by infiltration of eosinophils, with or without peripheral blood eosinophil count increased, often with abdominal pain disease, gastrointestinal symptoms due to infiltration of different parts and different. due to lack of etiology and triggering factors of the understanding, treatment mainly corticosteroids and other drugs on the immune system have also experimented with the application of but the effect is not yet sure. are on the epidemiology, pathophysiology, clinical features and treatment issues are reviewed. 1 Overview EG is a rare benign disease, the pathological to a large number of eosinophil gastrointestinal wall is characterized by common stomach and small intestine, colon rare, usually with or without the number of eosinophils in peripheral blood increased. Kaijser [1] in 1937 first described the disease in 1970, Klein et al [2] proposed a clinical classification of the disease, continue to use today. EG incidence rate is about (1 ~ 20/10 million [3]. As many patients are not diagnosed or unreported, the actual incidence is difficult to estimate. Any age may be the disease, the peak age of 30 to 50 years old. Gender not significant, slightly higher than men, the incidence of women [4]. 1.1 Etiology EG most cases is not clear risk factors, which may be related to other diseases, such as food allergies, infections stercoralis, amoeba, worms, and other gluten-related enteropathy. EG with certain medicines may also be relevant [4] . 1.2 Pathogenesis and pathophysiology EG to the organization is characterized by eosinophil infiltration, the pathogenesis is not clear. Generally thought to result from degranulation of eosinophils, the release