Ephedrine and dopamine spinal anesthesia for cesarean section compared the efficacy of low blood pressure.docVIP

 PAGE \* MERGEFORMAT 10 Ephedrine and dopamine spinal anesthesia for cesarean section compared the efficacy of low blood pressure [Abstract] Objective To compare the ephedrine and dopamine in the prevention of spinal hypotension during cesarean delivery results, and evaluate its adverse effects on the mother and fetus. Methods 60 patients were treated with bupivacaine for spinal anesthesia cesarean section were randomly divided into two groups, ephedrine group (n = 30) prophylactic ephedrine 10mg; dopamine group (n = 30) Dopamine 5g / (kg min) intravenous infusion. The incidence of adverse reactions observed , Evaluation of neonatal Apgar scores 1min and 5min, and umbilical arterial and venous blood gas analysis. Results The incidence of hypotension, ephedrine group (37%) than dopamine (60%) (P lt;0.05), ephedrine The average pH value of umbilical artery group and the 1min Apgar score less than dopamine group (P lt;0.05), 5min Apgar score was no significant difference between the two groups. Conclusion cesarean delivery spinal anesthesia to prevent hypotension dopamine ephedrine more effective than the two no difference between the incidence of adverse reactions, dopamine has little effect on the fetus, ephedrine has short-term impact on the fetus. [Keywords:] ephedrine; dopamine; cesarean section; hypotension; spinal anesthesia During spinal anesthesia for cesarean delivery on maternal and fetal hypotension are harmful, ephedrine is a non-catecholamine sympathomimetic drugs. The existing research suggests that ephedrine elevate blood pressure and protect the blood supply to the uterus and placenta mainly through the implementation of its -adrenergic-like effects [1]. studies suggest that small doses of dopamine used in epidural anesthesia during cesarean section, with a right hip appropriate booster and expansion of colloidal crystals, can maternal blood pressure, heart rate relative stable, fewer complications, better than ephedrine. This study was