Esophageal squamous cell carcinoma of HIF1α expression and the relationship between radiotherapy.docVIP

 PAGE \* MERGEFORMAT 2 Esophageal squamous cell carcinoma of HIF1α expression and the relationship between radiotherapy Authors: Zhang Hongzhen, Duan Xin-bo, Duan Zhe-ping, LIU Bin, ZHU Shu-chai [Abstract] Objective To study the esophageal squamous cell carcinoma of hypoxia inducible factor  1α (HIF  1α ) expression and the relationship between radiotherapy. Methods The immunohistochemical SP method detected 50 cases of esophageal biopsy with complete follow-up data of the receiving external beam radiotherapy for esophageal squamous cell carcinoma HIF  1α protein expression. Results 50 cases of esophageal squamous cell carcinoma Radiotherapy rate was 86%. HIF  1α was mainly expressed in esophageal squamous cell carcinoma of the nucleus, the positive expression rate of 68%; HIF  1α expression of positive and negative groups of patients with esophageal cancer after radiotherapy recent complete remission rate, median survival time and 95% confidence range of 18.75%, respectively, 10 (7.86,12.14) months and 81.25%, 25 (15.57,34.43) months, HIF  1α expression after radiotherapy group remission rate and survival time was significantly less than the negative group (P