Fluoroquinolones and reasonable application of adverse drug reactions.docVIP

 PAGE \* MERGEFORMAT 5 Fluoroquinolones and reasonable application of adverse drug reactions [Abstract] Objective To review the recent advances fluoroquinolones adverse drug reaction mechanism and the rational use. Method of access to the literature in recent years to conduct summarized. The results of fluoroquinolones on the human body organs and some organizations have a variety of adverse effects, while the gastrointestinal tract and central nervous system, the incidence of adverse reactions hold the top spot. Conclusion by strengthening the broad masses of medical workers to adverse drug reactions to fluoroquinolones awareness and understanding, thereby increasing the level of rational drug use. [Keywords:] fluoro-quinolone; adverse reaction; rational use of Clinical application of fluoroquinolone drugs are relatively wide range of antimicrobial drugs, is also a relatively new class of synthetic antibacterial agents [1]. However, the application of these drugs in recent years and makes adverse drug reactions have become increasingly prominent in the cure and save lives in patients with the same time, adverse health effects to patients, as well as endangering lives. To this end, this paper fluoroquinolones common adverse reactions, as well as a comprehensive overview of the rational use of to strengthen the broad masses of medical workers to adverse drug reactions to fluoroquinolones and thus raise awareness of the level of rational drug use. A fluoroquinolone drugs and clinical applications of Fluoroquinolones for the third generation of quinolone drugs, over the past 20 years, fluoroquinolones have listed are norfloxacin, ciprofloxacin and ofloxacin, due to further expansion of antibacterial spectrum against Gram-negative bacteria have a more strong antimicrobial activity. The recent development of levofloxacin, gatifloxacin and moxifloxacin raised against Gram-positive bacteria and atypical pathogens antibacterial activity, but antibacterial activity