Fluvoxamine and clomipramine treatment of obsessive-compulsive disorder.docVIP

 PAGE \* MERGEFORMAT 5 Fluvoxamine and clomipramine treatment of obsessive-compulsive disorder Authors: Li Hong Yuan Fu-hui LIU Chuan-zhi Li Rui [Abstract] Objective To investigate the Fluvoxamine and clomipramine in the treatment of obsessive-compulsive disorder in the clinical efficacy and safety. Methods 40 patients with OCD were randomly divided into study group and control group 20 patients were treated with fluvoxamine, clomipramine, observation 8 w. In the pre-treatment and treatment of 4 w, 8 w at the end with Yale  Brown forced to scale, side effects rating scale of clinical efficacy and adverse reactions. Results Study Group 8 w effective the end of 75% in the control group was 70%, no significant difference between the two groups (Pamp;gt; 0.05). Yale  Brown forced Scale Treatment of 4 w, 8 w than those of the end of the two groups before treatment there was a significant decrease (P all amp;quot;0.01), compared between the two groups there was no significant difference (P allamp;quot; 0.05). Study group the incidence of adverse reactions was lower than that of control, and the minor. Conclusion fluvoxamine treatment of obsessive-compulsive disorder with clomipramine very, high security, compliance is good. [Keywords:] Fluvoxamine; clomipramine; obsessive-compulsive disorder Clomipramine treatment of obsessive-compulsive disorder is a traditional drug of choice, but because of their more serious adverse reactions, which reduces the patient’s therapy compliance. There have been reported in the literature of new antidepressants tested in the treatment of obsessive-compulsive disorder to achieve a certain degree of efficacy [1] To this end, we apply Fluvoxamine and clomipramine conducted a controlled clinical study to investigate the clinical efficacy and safety of sex, now report on the results as follows. An object and methods 1.1 Object Selected in October 2004 ~ February 2006 in our hospital outpatient and inpatient treatment of 40 patien