HPLC determination of the Quartet on the stomach of Berberine Hydrochloride.docVIP

 PAGE \* MERGEFORMAT 7 HPLC determination of the Quartet on the stomach of Berberine Hydrochloride [Abstract]: Objective To establish a four-stomach capsule method for the determination of berberine hydrochloride. Methods HPLC method with octadecyl silane bonded silica as a filler, acetonitrile -0.05 mol / L potassium dihydrogen phosphate ( 25:75) as mobile phase, detection wavelength 230 nm. Theoretical plate number calculated by berberine should not be less than 3000. The results of the determination of linear linear range 0.201 6 ~ 1.008 μg (r = 0.999 8), recovery was 98.7%, RSD = 1.24% (n = 5). Conclusion The method is simple, accurate, and reproducible separation can be used for quality control of the Quartet stomach. [Keywords:] the Quartet Performance Liquid Chromatography determination of berberine hydrochloride capsules stomach Abstract: Objective To establish the content determination method of berberine hydrochloride in Sifangwei capsules. Methods HPLC method was used with octadecylsilane chemically bonded silica as the filler, acetonitrile-0.05 mol / L KH2PO4 solution (25:75) as the mobile phase, detective wavelength was 230 nm. The number of theoretical plates should not be less than 3 000. Results The content determination method has a good linear relation at the range of 0.201 6 ~ 1.008 μg (r = 0.999 8). The recovery rate was 98.7%, RSD = 1.24% (n = 5). Conclusion The method is simple, accurate, with good separation and reproducibility, and can be used for the quality control of Sifangwei capsules. Keywords:: HPLC, Sifangwei capsules, berberine hydrochloride, content determination Received four capsules contained in the stomach lt;lt;The Ministry of Health standards for traditional Chinese medicine prescription drugs agentsgt;gt; No. 14, the effectiveness of Liver and stomach acid pain, due to disharmony of liver and stomach pain, hyperacidity, indigestion, gastric and duodenal ulcers are. the former is no determination of the sta