Lipoprotein (a) The relationship between disease.docVIP

 PAGE \* MERGEFORMAT 12 Lipoprotein (a) The relationship between disease [Abstract] Objective To evaluate serum lipoprotein (a) [Lp (a)] and disease relationship. Methods 64 cases of healthy adults of serum Lp (a) normal control, collection of perianal abscess in 23 cases, 58 cases of hypertension, coronary heart disease in 25 cases of acute myocardial infarction in 6 cases, 10 cases of cerebral hemorrhage, cerebral infarction recovery 13 cases, diabetes mellitus 38 cases (32 patients with normal blood lipids and lipid abnormalities in 6 cases), 7 cases of chronic nephritis, chronic renal failure in 27 cases, severe hepatitis and cirrhosis in 15 cases, 58 cases of malignant tumors were determined Lp (a), respectively, compared with normal control group. One cases of acute renal failure, continuous measurement of serum Lp (a) and Cr concentrations. The results of perianal abscess, hypertension, coronary heart disease, acute myocardial infarction, cerebral hemorrhage, cerebral infarction recovery, diabetes mellitus (lipid abnormalities), chronic renal failure, severe hepatitis and cirrhosis, cancer and other diseases compared with normal controls, the difference There was a significant (P amp;lt;0.05), diabetes mellitus (lipid normal), chronic nephritis and normal controls, the difference was not significant (Pamp;gt; 0.05). Acute myocardial infarction and coronary heart disease, cerebral hemorrhage, cerebral infarction recovery, the difference was significant (P amp;lt;0.05), and coronary heart disease, cerebral hemorrhage, cerebral infarction between recovery, the difference was not significant (Pamp;gt; 0.05 ). Conclusions Serum Lp (a) synthesis by the liver, so patients with severe liver disease and cirrhosis of serum Lp (a) lower. Serum Lp (a) by interleukin -6 (IL-6) in control, while the IL-6 is mainly secreted by the endothelial cells, therefore vascular disease state (or capillary) of inflammation or damage of these diseases may be the serum Lp ( a) the