Medicine Man Red Hail ethanol extract of fruit Experimental Study of the treatment of primary dysmenorrhea.doc

 PAGE \* MERGEFORMAT 9 Medicine Man Red Hail ethanol extract of fruit Experimental Study of the treatment of primary dysmenorrhea Author: Tong Li Lanfang Lucy Liu Jiming Chen Guanghui [Abstract] Objective To observe the red hail ethanol extract of the fruit of the impact of primary dysmenorrhea. Methods of oxytocin-induced mouse model of primary dysmenorrhea and in vitro uterine smooth muscle spasm, to mouse writhing latency, writhing frequency and in vitro uterine smooth muscle contraction amplitude and frequency as an index to evaluate red hail ethanol extract of the fruit therapeutic effects of primary dysmenorrhea. Results of ethanol extract of red hail fruit can significantly extend the oxytocin-induced writhing response in mice the incubation period, reducing the number of writhing response, and blank control group were significantly significance (P amp;lt;0.05 or P amp;lt;0.01); to reduce shrinkage Gong Su-rise rate of uterine contraction in vitro to reduce the contraction frequency compared with the control group the difference was significant (P amp;lt;0.05 or P amp;lt;0.01). Conclusion Red Hail fruit alcohol extract on oxytocin-induced mouse primary dysmenorrhea significant therapeutic effect. [Keywords:] red hail ethanol extract of primary dysmenorrhea fruit Red Hail fruit (Manchu: Fu Yue to package Nu Yen Tu, r.) is the red Cucurbitaceae hail Thladiantha dubia Bune mature dry fruit, mainly distributed in North China, Northeast China, Inner Mongolia and other regions rich in resources for the treatment of dysmenorrhea, breast swelling and pain, rheumatism and other pains, in the Manchu people has been practiced for a long time effect is significant, and no obvious side effects. Previous studies have shown that the water extract of red fruit hail a clear analgesic effect [1]. To verify the efficacy of the treatment of primary dysmenorrhea, provide a scientific basis for clinical application, this paper red fruit hail the role of the treatment of p