Milk Preparation Process Kang Dispersible Tablets.doc

 PAGE \* MERGEFORMAT 16 Milk Preparation Process Kang Dispersible Tablets Author: Zhong Fusheng, bell small groups, Caiqing Shun, Peng Rui 【Abstract】 Objective To prepare to meet the requirements of the milk out of health dispersible preparations to carry out research preparation process. Methods to spread uniformity, tablet hardness, friability, etc. as an indicator to compare the different prescription and processes such as different types and proportion of disintegrating agent, thinner, adhesives and various tableting technology such as pressure and hardness of control, disintegrants to join method, particle size and moisture control. Results disintegrating agent is cross-linked polyvinylpyrrolidone (cross-linked PVP), the dosage powder, 75%; thinner as microcrystalline cellulose, the dosage for the powder to 25%; adhesive was 10% aqueous solution of PVP K30, the dosage 6% of the powder; hardness control as 4 ~ 9 kg; 90% disintegrating agent in Canada, 10% plus; particle size of 35 mesh; water is less than 5.0%. Conclusion The process of pilot production products out of the targets can comply with the requirements may be feasible, reproducible, is suitable for industrial production. Keywords: breast Kang Dispersible Tablets; dispersion uniformity; Friability; disintegrating agent; Thinner Abstract: ObjectiveTo make the qualified Rukang Dispersible Tablets, we carried out a detailed reasearch. MethodsWith disperal uniformity, rigidity, brittleness as the targets, we compared different kind ingrents (such as different dispersants, thinners, emplastics) and preparation process (such as the control of brittleness, granularity moisture). ResultsWe chose PPVP as dispersant (by 75%), MC as rigidity by (25%), 10% PPVPK30 as brittleness (by 6%), brittleness under 4kg ~ 9kg, granularity 35 mesh, moisture under 5.0%. ConclusionThe mass trail products made accord to the best preparation meet to the legal regulations. The process is operatable