Monoclonal antibodies in the treatment of tumors of the research.docVIP

 PAGE \* MERGEFORMAT 12 Monoclonal antibodies in the treatment of tumors of the research Authors: Hai-Dong Yang Ao FAN Yi-jun Qin Luo Zhixiang Abstract overview of monoclonal antibodies in the treatment of tumors are reviewed. Monoclonal antibodies in cancer diagnosis and treatment have been widely used research and clinical application of its technology has achieved significant breakthroughs. Keywords: monoclonal antibody tumor antibodies Monoclonal antibody (monoclonal antibody) Since their discovery, has become specific human cells to identify and combat the invasion of alien pathogen resistance resulting from a biological material, called monoclonal antibody. It has high sensitivity, specificity, high efficiency, low toxicity and so on. Monoclonal antibody is currently mainly used for diagnosis of various types of disease, drug preparation technologies are increasingly sophisticated. Monoclonal antibody agents research has achieved the desired results. Currently, worldwide more than 500 kinds of diagnostic and therapeutic monoclonal antibody market, more than 100 kinds of clinical research for the [1], according to statistics, as of 2004  02, the U.S. FDA has approved for clinical treatment of 18 in vivo monoclonal antibody drugs; China has also successfully developed more than 300 kinds of monoclonal antibodies, and has been used in cancer therapy. Status of a tumor therapy Cancer is a serious threat to human health, genetic disease is a somatic cell of acquired changes in DNA leading to uncontrolled cell proliferation, and this proliferation continued invasion of the surrounding normal tissue due to [2]. In recent years, cancer treatment has become a large number of medical workers in the research hotspot, in which monoclonal antibody targeted therapy for cancer has shown good prospects. His research focused mainly on the antibody and chemical drugs, enzymes, radionuclides, toxins and biological agent