Naloxone treatment of acute alcoholism observation of 68 cases.doc

 PAGE \* MERGEFORMAT 6 Naloxone treatment of acute alcoholism observation of 68 cases [Paper Keywords:] Naloxone; acute alcoholism; treatment [Abstract] Objective: To evaluate the efficacy of naloxone in treatment of acute alcoholism and safety. Methods: 68 cases of acute alcoholism in patients given conventional therapy on the basis of naloxone treatment, to observe the conscious time. Results: 47 patients were awake within 1 h in 21 patients within 4 h in the sober, with a total effective rate was 100%. Conclusion: The efficacy of naloxone in the treatment of acute alcoholism in patients with significant, worthy of clinical application. Our hospital from January 2005 ~ January 2008 were treated 68 cases of acute alcoholism, we used naloxone hydrochloride injection in the treatment received good results, are summarized below. A clinical data 1.1 General information: acute alcoholism in 68 patients, male 50 cases and 18 female, aged 19 to 47 years, an average of 33 years. Alcohol consumption is equivalent to 52-degree wine 200 ~ 800 ml. Poisoning to treatment time of 0.5 ~ 5 h, an exciting period at the time of treatment in 20 cases, ataxia period of 21 cases, drowsiness period of 27 cases of coma. 1.2 diagnostic criteria [1]: (1) before onset of excessive alcohol consumption history; (2) breathing, vomit, there is the smell of alcohol; (3) central nervous system stimulant or inhibition, with symptoms such as ataxia, or drowsiness moderate or severe poisoning was unconscious; (4) exclusion of drugs, chemical gases and other factors caused by drowsiness, coma, no other complication. According to the extent of alcoholism in clinical practice can be divided into mild, moderate and severe. Mild: The patient excitement, headache, dizziness, fatigue, loss of self-control, self-inductance euphoric, speech increased around the tongue, and sometimes rude, easy emotion, facial flushing or pale, with a down-exhaled breath. Moderate: The patient incoordinatio