Of meglumine cyclic adenylate in the United GIK on patients with acute organophosphorus pesticide poisoning QT dispersion_0.docVIP

 PAGE \* MERGEFORMAT 7 Of meglumine cyclic adenylate in the United GIK on patients with acute organophosphorus pesticide poisoning QT dispersion Of: Yang Zhou, Dengyou Hui, Li Feng Cui, Lord Kennedy, Rong Gao, Huang Yue [Abstract] Objective To observe cAMP meglumine combination with GIK in acute organophosphorus pesticide poisoning (AOPP) in patients with QT dispersion. Methods 59 cases of AOPP were randomly divided into treatment group (30 cases and the control group (29 patients in the treatment of the same treatment group on the basis of polarized liquid and cAMP 120mg intravenous infusion of meglumine, 1 day, 7 day a course of treatment. in the first 1,3,4,7 days EKG should be done to record ECG changes. Results After treatment, the 4th day, 7 days QTd value of the two groups decreased significantly compared with the time of admission, and treatment group than in the control group decreased more significantly (P lt;0.01. arrhythmia treatment group number of cases was significantly less than the control group (P lt;0.05. Conclusions of meglumine cyclic adenylate AOPP patients treated with GIK, QTd of patients can be significantly improved to reduce the incidence of arrhythmias. [Keywords:] poisoning and cAMP meglumine, polarized liquid, organic phosphorus insecticide Acute organophosphorus pesticide poisoning (AOPP poisoning caused the heart damage is one of the causes of death in patients, and prolonged QT AOPP patients is to predict an important indicator of cardiac arrest [1]. Studies have shown that [2], QT dispersion (QTd closely related with the malignant arrhythmia. In recent years our hospital with meglumine cyclic adenylate AOPP with GIK on myocardial injury in the toxic treatment, good results are reported below. 1 Materials and Methods 1.1 General data collection in January 2005 ~ December 2007 AOPP in our hospital 59 patients, myocardial damage to the standard ECG [3]. Premorbid history had no structural heart disease and arrhyt