Scutellaria baicalensis from different extracts of influenza virus in rats_0.docVIP

 PAGE \* MERGEFORMAT 10 Scutellaria baicalensis from different extracts of influenza virus in rats [Abstract] Objective To compare the different sources skullcap extract (Hebei, Shanxi, Dalian) of influenza virus strains of influenza A rat lung adaptation (FM1) the death of mice infected with the protection and inhibition. Methods FM1 infected mice as animal model, 1 h after the administration of the infection to mortality, average survival days, the lung index for the evaluation, observations from different sources skullcap extract in mice against influenza virus. The results from different sources skullcap extract can reduce the mortality rate in mice infected with influenza virus (P lt;0.05), prolonged the survival time (P lt;0.05), decreased lung index (P lt;0.05). Conclusion skullcap extracts from different sources are good the role of anti-influenza virus infection, of which the water extract of Scutellaria Hebei group best. [Keywords:] skullcap extract, influenza virus, animal model Abstract: Objective To compare the effect of different sources extracted scutellaria (Hebei, Shanxi and Dalian) on the death-protection and inhibition of FM1 infected mice. Method As animal model, FM1 infected mice was treated an hour after infection. Indexes including mortality, average survival time, lung index were observed to evaluate the effect of different sources extracted scutellaria on anti-influenza virus. Result Different sources extracted scutellaria reduced mortality (P lt;0.05), prolonged the survival time of mice (P lt;0.05) and decrease lung index (P lt;0.05). Conclusion Different sources extracted scutellaria have anti-influenza virus effect, and aqueous extract of Hebei scutellaria is the best. Keywords:: scutellaria extract, influenza virus, animal model Labiatae Scutellaria plants for the dry root of Scutellaria, only contained in the lt;lt;Shen Nong’s Herbal Sutra “gt;, a heat dampness, purging fire detoxification, bleeding tocolysis eff