Scutellaria decompression Softening Process steam.docVIP

 PAGE \* MERGEFORMAT 9 Scutellaria decompression Softening Process steam [Abstract] Objective To study the skullcap decompression process steam to soften. Methods Pieces of baicalin content and appearance of a comprehensive evaluation index score, using orthogonal design skullcap steaming the optimum decompression. The optimum result for the vacuum of -0.08 MPa, temperature 100 ℃ , time 20 min. Concluded Scutellaria softening processes provide an objective quantitative indicators. [Keywords:] Scutellaria baicalensis Georgi; decompression steam; softening process; orthogonal test 1 Materials 1.1 The test drug Scutellaria medicine company purchased from Hunan Province by Hunan University of Chinese Medicine First Affiliated Hospital, Bei Zhou, deputy director of the new pharmacist identification, for origanum skullcap Scutellaria baicalensis Georgi dry root. This study selected sub-qin. Baicalin reference substance (China Pharmaceutical and Biological Products Institution, for the determination of use); HPLC pure methanol, phosphoric acid as a superior grade of pure water for the self-re-distilled water, the remaining reagents were analytical pure. 1.2 Instrument Agilent 1100 HPLC (Agilent); AY-120 electronic analytical balance (Shimadzu); SHB-Ⅲ recycled water Multi-purpose vacuum pump (Zhengzhou Great Wall); SK5200H KUDOS ultrasonic cleaner (Shanghai Branch guide); DHG blast-9076A-type electric constant temperature oven (Shanghai Jing-hong); decompression device (own modification). 2 Methods and Results 2.1 Experimental study enzyme medicinal Scutellaria Take the net skullcap herbs 100 g, cut into pieces about 3 mm thick, divided into two copies, one copy directly at 60 ℃ drying 4 h, standby; the other an amount of cold water were added at 25 ℃ to place 24 h, so that hydrolysis to observe the aspect color change, take out, at 60 ℃ drying 4 h, standby. Aspect will be two copies of sample colors and baicalin comparison of the results in Table 1. Th