Selective chemical bile duct embolization for chemical hepatectomy in experimental study.docVIP

 PAGE \* MERGEFORMAT 5 Selective chemical bile duct embolization for chemical hepatectomy in experimental study [Abstract] Objective: To observe the method of lines of different chemical bile duct embolization after embolization of liver function and histological changes of chemical bile duct embolization for chemical hepatectomy the feasibility and efficacy. Methods: anhydrous ethanol or anhydrous alcohol medical biological glue joint biological glue in rat bile duct selective chemoembolization, observed postoperative liver function, hepatic mass and pathological changes. Results: In addition to ethanol plus biological glue group 4 weeks alkaline phosphatase (ALP) is still higher than normal, each treatment group, ALP, alanine aminotransferase (ALT) and total bilirubin (TB) are the basic normal or slightly higher than normal. The treatment group showed significant atrophy of liver fibrosis in the mid-size, down to a normal 1 / 3 1 / 2, while non-therapeutic hepatic hypertrophy, volume increased 1.5 2.0 times; pathological observations indicate that bile duct wall skin after chemoembolization structure disappeared, lymphocyte infiltration around the wall, the wall fibrosis, periportal fibrous septa with obviously enlarged, fibroblast proliferation, a large number of collagen fibers generated a large number of bile duct proliferation, hepatic lobule structure disappeared, reduce the number of liver cells. Conclusion: Selective biliary chemoembolization are likely to be the effect of chemical hepatectomy. Ethanol co-biliary drainage areas of biological glue to shrink liver fibrosis best results. Pure ethanol for chemical-induced liver resection can be effective, and less impact on the body and liver function. [Keywords:] bile duct embolization for liver resection in rat intrahepatic bile duct stones Partial liver resection is the treatment of the primary means of intrahepatic bile duct stones, but even the rules of the liver sections and sub-hepatic resection,