The mechanism of corpus luteum degeneration.docVIP

 PAGE \* MERGEFORMAT 19 The mechanism of corpus luteum degeneration Keywords:: degradation of apoptotic luteal prostaglandins Follicle after ovulation a series of drastic changes, its granulosa cells or theca cells into luteal cells, a process known as follicular luteinization. Corpus luteum of the ovarian cortex results in the formation of a true endocrine gland that the corpus luteum. The vast majority of animals, corpus luteum formed mainly by the granule cell transformation, but the primate and rat luteal cells are of the envelope components. After ovulation in the cavity of the original follicle proliferation of granulosa cells were quickly filling, the particles when cells in the corpus luteum of the original diameter of 12 ~ 14μ m, increased to 35 ~ 50μ m. Cytoplasmic and nuclear larger proportion of the cytoplasm contains secretory granules and fat droplets increased, and contains a yellow pigment, which called the corpus luteum. Mitochondrial morphology also changed, rough endoplasmic reticulum disappeared, while smooth endoplasmic reticulum increased, corresponding with these morphological changes is equipped with luteal cells secrete progesterone function. Corpus luteum the existence of a certain time frame, depending on whether the animal had been pregnant. Primate ovulation, the corpus luteum to maintain its shape and function of about 2 weeks, and then, their cell function and structure are spontaneous recession. In case of pregnancy, the human chorionic gonadotropin can continue to maintain its structure and function. Non-human primates and human corpus luteum in the pituitary luteinizing hormone (lH) produced under the control of hormones, lH pulse frequency from the mid-to late luteal began to decline, but the exogenous high-frequency pulse-lH non-renewal of luteal life span [1 ]. This shows that the luteal phase is the duration of the intrinsic characteristics of corpus luteum. Corpus luteum at the end of degradation of luteal cells, proge