国产与进口托瑞米芬治疗乳腺癌的成本-效果分析.pdfVIP

吗泸 ,.鹏 t pqh 巳 ~-~.----=、-~- -...._.--，~~_.~- 幽 ~→--年....翩翩........俨 b 一吨 捕_.......~~......，.‘ 自~- 画凰 翩翩翩..... 幽 ...._ - - - ‘ 【临床药学】 ·论文· 国产与进口托瑞米芬治疗乳腺癌的成本-效果分析 林燕，陶红慧*，严楚 J烦，陈铮，戴佳琳 (J工海市黄浦区中心医院药剂科，上海 200002) 摘要 2 目的比较同产与进口托瑞米芬治疗乳腺癌的成本·效果。方法 80 例乳腺癌患~.随机分为 2 组，国产托瑞米芬组 50 例，进口托瑞米 51二组 30 例。两组病例均为 60 mg ，一日 l 次用药，疗手里口个月，回顾性评价内组成本·效果。结果国 ZNC-NEUME产和进口托瑞米芬治疗乳腺癌的临床有效率和不良反应发生率差异无统计学意义，平均药品成本分别为 3238.08 元和 4512.∞元，统计学差异显著 (P 0.0 1)。结论成本-效果分析提示，国产托瑞米芬治疗乳腺癌安全布效，且较迸口托瑞 米芬更为经济。 关键词 z 托瑞米芬:乳腺癌:成本，放果分析 中图分类号: R977. I2: R737.9: R956 文献标志码 :A 文章编号: 1672-9188(2012)08-0478-04 Cost-efficacy analysis of domestic and import toremifene in the treatment ofbreast cancer LIN Yan, TAO Hong-huì, YAN Chu-shun, CHEN Zheng, DAI Jia-Iìn (Department 01 Pharmacy. Shanghai Huangpu Districl Central Hospital, Shanghai 200002, China) Abstract: Objective To compare the cost-efficacy of domestic and ìmport toremìfene in the treatment ofbreast cancer. Methods Eìghty patients wìth breast cancer were randomly dìvìded into two groups, 30 subjects in ìmport toremìfene group and 50 subjects in domestìc toremìfene group. Both groups were gìven 60 mg once a day for 12 months. The cost? efficacy was evaluated retrospectìvely. Results There was no significant difference in clinical effective rate a