Preventing Childhood Malaria in Africa by Protecting Adults from Mosquitoes with Insecticide-Treated Nets 英文参考文献.docVIP

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Preventing Childhood Malaria in Africa by Protecting Adults from Mosquitoes with Insecticide-Treated Nets 英文参考文献.doc

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Preventing Childhood Malaria in Africa by Protecting Adults from Mosquitoes with Insecticide-Treated Nets 英文参考文献

o PL SMEDICINE PreventingChildhoodMalariainAfrica byProtectingAdultsfromMosquitoes withInsecticide-TreatedNets Gerry F.Killeen1,2*,Tom A.Smith3,Heather M.Ferguson1,4,5,Hassan Mshinda1,Salim Abdulla1,Christian Lengeler3, Steven P.Kachur1,6 1 Ifakara Health Research and Development Centre, Ifakara, Morogoro, United Republic of Tanzania, 2 Department of Biological and Biomedical Sciences, University of Durham, Durham, United Kingdom, 3 Department of Public Health and Epidemiology, Swiss Tropical Institute, Basel, Switzerland, 4 Division of Infection and Immunity, GlasgowUniversity,Glasgow,UnitedKingdom,5DivisionofEnvironmentalandEvolutionaryBiology,GlasgowUniversity,Glasgow,UnitedKingdom,6UnitedStatesPublic HealthServiceCommissionedCorpsandMalariaBranch,DivisionofParasiticDiseases,CentersforDiseaseControlandPrevention,Atlanta,Georgia,UnitedStatesofAmerica Funding:Thisstudywassupported bySwissNationalScience ABSTRACT Foundation(awards2200C0-10594 and3270-059541-99),Billand MelindaGatesFoundation(award 39777),theBiotechnologyand BiologicalResearchCouncilofthe UnitedKingdom(DavidPhillips FellowshipawardedtoHMF),and theWellcomeTrust(ResearchCareer DevelopmentFellowshipnumber 076806awardedtoGFK).These fundingagencieshadnoroleinthe studydesign,datacollctionand analysis,decisiontopublish,or preparationofthemanuscript. Background MalariapreventioninAfricameritsparticularattentionastheworldstrivestowardabetter life for the poorest. Insecticide-treated nets (ITNs) represent a practical means to prevent malaria in Africa, so scaling up coverage to at least 80% of young children and pregnant womenby2010isintegraltotheMillenniumDevelopmentGoals(MDG).Targetingindividual protection to vulnerable groups is an accepted priority, but community-level impacts of broaderpopulationcoveragearelargelyignoredeventhoughtheymaybejustasimportant. We therefore estimated coverage thresholds for entire populations at which individual- and community-level protection are equivalent, representing