Quality of Life and Related Factors among HIV-Positive Spouses from Serodiscordant Couples under Antiretroviral Therapy in Henan Province, China 英文参考文献.docVIP
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Quality of Life and Related Factors among HIV-Positive Spouses from Serodiscordant Couples under Antiretroviral Therapy in Henan Province, China 英文参考文献
QualityofLifeandRelatedFactorsamongHIV-Positive
SpousesfromSerodiscordantCouplesunder
AntiretroviralTherapyinHenanProvince,China
DuoShan1,ZengGe2,ShuaiMing1,LanWang1,MichaelSante1,WenshengHe3,JianpingZhou3,
ShanglongLiu4,LuWang1*
1National Center for AIDS/STD Control Prevention, Chinese Center for Disease Control Prevention, Beijing, China, 2Fuwai Hospital and Cardiovascular Institute,
ChineseAcademyofMedicalSciencesandPekingUnionMedicalCollege,Beijing,China,3ZhumadianCenterforDiseaseControlandPrevention,ZhumadianCity,Henan
Province,China,4TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan,China
Abstract
Objective: To describe the quality of life and related factors in HIV-positive spouses undergoing ART from discordant
couples.
Methods: A cross-sectional study was conducted among 1,009 HIV-positive spouses from serodiscordant couples in
Zhumadian,HenanProvince,betweenOctober1,2008andMarch31,2009.HIV-positivespouseswereinterviewedbylocal
healthprofessionals.QualityoflifewasevaluatedbyWHOQOL(ChineseVersion).Amultiplelinearregressionmodelwas
usedtoanalyzetherelatedfactors.
Results:Themajorityofsubjectswerefemale(56.39%),hadreceivedahighschooleducation(44%),wereofHanethnicity
(98.41%),andwerefarmers(90.09%);themediantimeperiodofreceivingARTwas3.92years.Thephysical,psychological,
social, and environmental QOL scores of the subjects were 12.9161.95, 12.3561.80, 13.9662.43, and 12.4561.91
respectively. The multiple linear regression model identified the physical domain related factors to be CD4 count,
educationallevel,andoccupation;psychologicaldomainrelatedfactorsincludeage,educationallevel,andreportedSTD
symptom; social domain related factors included education level; and environmental domain related factors included
educationlevel,reportedSTDsymptoms,andoccupation.
Conclusion: Being younger, a farmer, having a lower level of education, a reported STD symptom, or lower CD4 count,
coulddecreaseone’squalityoflife,suggestingthattheuseofblanketARTprograms
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