Spontaneous rupture of malarial spleen two case reports and review of literature 英文参考文献.docVIP

/content/4/5/309 Primary research Spontaneous rupture of malarial spleen: two case reports and review of literature Yusuf Yagmur, Ismail Hamdi Kara, Mustafa Aldemir, Hüseyin Büyükbayram, Ibrahim H Tacyildiz and Celalettin Keles Dicle University, Faculty of Medicine, Diyarbakir, Turkey Received: 26 June 2000 Accepted: 11 July 2000 Published: 10 August 2000 Crit Care 2000,4:309–313 ? Current Science Ltd (Print ISSN 1364-8535; Online ISSN 1466-609X) Abstract Malaria has long been among the most common diseases in the southeast Anatolia region of Turkey. In 1992, 18676 cases were diagnosed in Turkey, and Diyarbakir city had the highest incidence (4168 cases), followed by SanliUrfa city (3578 cases). Malaria was especially common during 1994 and 1995, with 84345 and 82094 cases being diagnosed in these years, respectively. Spontaneous rupture of malarial spleen is rare. We saw two cases during 1998, which are reported herein. Both patients were male, and were receiving chloroquine treatment for an acute attack of malaria. One of the patients had developed abdominal pain and palpitations, followed by fainting. The other patient had abdominal pain and fever. Explorative laparotomy revealed an enlarged spleen in both patients. Splenectomy was performed in both patients. We have identified 15 episodes of spontaneous rupture of the spleen in the English language literature published since 1961. Because of increased travel to endemic areas and resistance to antimalarial drugs, malaria is a major medical problem that is becoming increasingly important to surgeons worldwide. Malaria is a particularly important problem in the southeast Anatolia region of Turkey. Prophylactic precautions should be taken by tourists who travel to this region, especially during the summer. Keywords: malaria, prophylactic precautions, ruptured spleen Introduction Case reports Involvement of the spleen in malaria that results in splenome