儿童骨龄评估与终高预测方法初探_1.docVIP

儿童骨龄评估与终高预测方法初探 作者：王秀民，何美朵，王伟，王德芬 【关键词】 骨龄评估 　【摘要】 目的 比较四种常用的骨龄评估法（BP、CHN、TW2、TW3）对骨龄评估结果的差异性；并比较用其对应的成人身高预测PAH法（BP、CHN、TW2-叶氏、TW3）预测不同病种患儿成人身高结果与实获终身高（NAH）的差异性。 方法 身高测量用墙式测高器，手及腕部骨龄X线片投照按标准技术，骨龄评估：使用上海瑞金 医院 放射科设计的TW2、CHN骨龄评分软件及GP图谱，TW3根据TW2也用 计算 机辅助评估，用SPSS 10.0软件，计量资料以（x±s）表示，做单因素方差 分析 （ANOVA），组间差异用LSD方法分析。结果 在各年龄四种骨龄评估法（GP、CHN、TW2、TW3）结果差异无显著性（P＞0.05）；四种方法（BP、TW2-叶氏、CHN、TW3）预测终身高：BP法与预测终身高有正负相关即不同正相关性（R=0.95，P≤0.01），TW3与终身高也有正相关性R=0.923，P＜0.01，如将患者分组，矮小组：TW2与NAH有差异（F=4.35，P=0.039），NAH与BP和CHN有相关性（R=0.918，P≤0.001），早熟组：三种方法（BP，CHN，TW2-叶氏），与NAH差异无显著性，相关系数分别为R=0.981，P＜0.01，R=0.982，P＜0.01，R=0.988，P≤0.01；TS组:BP与NAH差异无显著性（R=0.956，P＜0.05），CHN与NAH不相关（R=0.623，P＜0.05）。结论 （1）骨龄评估在小年龄（≤10岁），TW3与GP方法最接近。在大年龄评估中四种方法均可采用。（2）采用骨龄预测终身高TW3和BP法最接近NAH，但在不同疾病BP法更接近NAH。 　　【关键词】 骨龄评估；近似终身高；预测终身高 　　Methods of childrens bone age assessment and prediction of adult hEight 　　【Abstract】 Objective To compare the different results of four common methods of bone age estimation (GP, CHN, TW2, TW3）,and compare the differences between NAH and the predictive hEIght by using the method of PAH (BP, CHN, TW2-Ye, TW3）.Methods The heights were measured by instruments, and bone age of hand and wrist by X-ray according to standard technology. Bone age estimations were performed by using TW2, CHN bone age estimation software and GP map desired by Radiological Department of Shanghai Ruijin Hospital.TW3 estimation was done according to TW2 with computer assisting. Results was presented by χ2x±s. The software of SPSS 10.0 was used to statistically analysed with method of ANOVA. The differences among the groups were analysed by using the method of LSD. Results At different ages, the results of four methods of bone age estimation (GP, CHN, TW2, TW3） had no difference (P＞0.05）. BP method had positive correlation with predictive height (R=0.95,P≤0.01） and so was method of TW3 and predictive height (R=0.923, P≤0.01）. Conclusion (1） At younger age (≤10 years old）, the results of TW3 and GP are the closest to