从毒论治糖尿病并下肢动脉粥样硬化性疾病的临床探究.pdfVIP

提 要 目的：通过解毒通脉饮对糖尿病并下肢动脉粥样硬化性疾病(Lower Extremity Atherosclerotic Disease，LEAD)进行干预的临床研究，对从毒论治糖尿病并下肢动 脉粥样硬化性疾病进行探讨，并观察临床疗效，以期为治疗提供一定的思路和方法。 方法：将 60例毒壅经脉型糖尿病LEAD患者随机分为治疗组和对照组，治疗组服用解 毒通脉饮，对照组服用糖脉康颗粒，疗程均为180天。观察两组患者治疗前后双下肢 动脉彩超、临床症状、C反应蛋白、空腹血糖、血脂等指标的变化。结果：两组患者 的双下肢动脉彩超、临床症状、C反应蛋白、空腹血糖、血脂等均有了明显改善，且 两组有差异（P0.05），治疗组疗效优于对照组。试验期间未发现不良反应。结论： 解毒通脉饮可以改善糖尿病 LEAD 患者的下肢动脉粥样硬化情况，改善患者的临床症 状，达到早期防治LEAD的效果，减少患者坏疽及截肢的发生。 关键词 糖尿病并下肢动脉粥样硬化性疾病；解毒通脉饮；双下肢动脉彩超；临 床研究 The clinical research of treating from du in Diabetic lower extremity atherosclerotic disease Speciality: Clinical medicine of TCM Author: Ma Xiaoming Tutor: Professor Zhang Juan Abstract Objective:By the clinical research of JieDuTongMaiYin in interfering Diabetic Lower Extremity Atherosclerotic Disease(LEAD),to explore treating from du in LEAD and reduce the incidence rate of diabatic gangrene and amputation,in order to treat Diabetic LEAD to provide certain theoretical basis and practical thought and method.Methods:60 patients who suffered from LEAD were randomly divided into two groups including the treatment group and the control group.The treatment group was given JieDuTongMaiYin,while the control group was given TangMaiKang granule.180 days later,we observed the change of Pair of lower limbs artery with Color Doppler ultrasound , clinical symptom, Carbohydrate metabolism index, blood-fat metabolism index and C reaction protein between the treatment group and the control group.Results:The two group’s Pair of lower limbs artery with Color Doppler ultrasound , clinical symptom, Carbohydrate metabolism index, blood-fat metabolism index and C reac