化瘀杀胚汤配合甲氨蝶呤及米非司酮治疗未破损期异位妊娠的临床研究.pdfVIP

提 要 目的：探讨化瘀杀胚汤配合甲氨蝶呤(MTX)及米非司酮保守治疗未破损期异位妊 娠的临床疗效及作用机制。 材料与方法：将 60 例未破损期异位妊娠患者随机分为对照组（30 例，甲氨蝶呤 及米非司酮治疗）和治疗组（30 例，化瘀杀胚汤配合甲氨蝶呤及米非司酮治疗），观 察两组的临床疗效、血β-HCG 下降至正常所需时间、异位妊娠包块吸收时间及治疗 后输卵管通畅情况方面的差异。 结果：治疗组治愈率为 93.33%，对照组治愈率为 70.00%，两组比较差异具有显 著性(P0.05)，治疗组疗效优于对照组；治疗组血β-HCG 下降至正常的时间与对照 组比较缩短，差异具有显著性(P0.05) ；治疗组盆腔内异位妊娠包块吸收时间与对照 组比较缩短，差异具有显著性(P0.05) ；患侧输卵管通畅性检测治疗组优于对照组， 差异具有显著性(P0.05) 。 结论：化瘀杀胚汤配合甲氨蝶呤(MTX)及米非司酮可有效降低血β-HCG 水平， 改善盆腔血液循环状况，促进异位妊娠包块的软化、吸收及消散，达到杀胚消癥的目 的，有利于改善患者的临床症状和体征，最大限度的恢复患者的生殖功能和身体健康。 关键词 化瘀杀胚汤，甲氨蝶呤, 米非司酮，异位妊娠，临床观察 HuaYuShaPei Decoction combined methotrexate and mifepristone therapy clinical observation of ectopic pregnancy abstract Speciality：Gynecology of Traditional Chinese Medicine Author ：Xu MingXiao Tutor：Professor Liu Jinxing Abstract Objective:discussion of huayushapei decoction combined methotrexate and mifepristone conervative treatment of ectopic pregnancy clinical efficacy and mechanism of action. Method:60 cases of unruptured ectopic pregnancy patients receiving were randomly divided into control group(a singal methotrexate therapy ) and treatment group (traditional Chinese medicine combined methotrexate therapy).The clinical efficacy of the two groups were observed , the serum β HCG dropped to normal time required for tubal pregnancy, the mass absorption time and after treatment of tubal patency. Results:the trestment success rate for the group,the contral group 93.33% success rate for 70.00%,rate comparison,both groups have significant differences(P0.05); treatment group , serum β HCG dropped to normal and pelvic ectopic pregnancy in the mass absorption compared with the control group , the time were shortened , the difference was significant (P0.05);ipsilateral tubal patency detected treated gr