化瘀祛斑法治疗黄褐斑临床疗效观察和其对性激素水平的影响.pdfVIP

提 要 目的：观察化瘀祛斑法治疗黄褐斑的临床疗效，初步探讨化瘀祛斑汤联合祛斑面 膜的作用机理。方法：60例病例被随机分成2组，治疗组30例服用化瘀祛斑汤（由当 归、生地、川芎、赤芍、白芍、茯苓、炒白术、柴胡、香附、丹皮、丹参、炙甘草组 成）联合外用祛斑面膜（由茯苓、白芍、当归免煎颗粒组成），对照组30例口服维生 素C、维生素E联合外用复方维A酸霜，主要观察临床疗效及不良反应，同时观察治疗 组治疗前后血清性激素水平的变化。结果：总有效率治疗组为80.00%，对照组为 50.00%，两组比较，差异有显著性意义（P0.05）。基本痊愈率治疗组为30.00%，对 照组组为13.33%，两组比较，无显著性差异（P0.05）。两组治疗前后皮损总积分均 明显下降，治疗前后比较，差异均有显著性意义（P0.05）。两组治疗前后总积分下 降差值比较，差异有显著性意义（P0.05）。治疗组治疗后血清雌二醇(E2)、黄体生 成素(LH)、卵泡刺激素(FSH)显著降低，治疗前后比较，差异有显著性意义(P0.05))。 结论：化瘀祛斑汤联合祛斑面膜治疗黄褐斑有较好的疗效，能明显减轻黄褐斑的临床 症状，化瘀祛斑汤联合祛斑面膜能够调节E2 、FSH、LH水平。 关键词 黄褐斑；化瘀祛斑汤；祛斑面膜；临床疗效；性激素 The clinical efficacy Observation on Treatment of Chloasma with HuaYuQuBanTang Combined with QuBan Mask and The Change of Serum Gonada Hormone Speciality：Dermatology ，Surgery of TCM Author ：Jiang Mingjun Tutor ：Professor Song Yeqiang Abstract Objective: To observe the clinical efficacy and the impact of serum gonada hormone on treatment of chloasma with HuaYuQuBanTang combined with QuBan mask, and Initially study its therapeutic mechanism. Methods : 60 cases were randomly divided into tow groups, namely the group of treatment group （HuaYuQuBanTang combined with QuBan mask ）, the group of matched group （Vc 、V with compound V creams ）, the E A clinical efficacy and side effect were observed and compared. At the same time, Before and after treatment the level of main serum gonada hormone was observed. Results : The total effective rate of the group of treatment group was 80.00%, The total effective rate of the group of matched group was 50.00%, After statistical analysis, the group of treatment group were better than matched group (P0.05). The cure rate of the group of treatment group wa