化瘀止血汤联合米非司酮保守治疗不稳定型异位妊娠的临床探究.pdfVIP

提 要 目的：探讨化瘀止血汤联合米非司酮保守治疗不稳定型异位妊娠的临床疗效及作 用机理。方法：将异位妊娠患者60例，随机分治疗组和对照组，每组各30例。治疗 组予米非司酮及化瘀止血汤；对照组予米非司酮及宫外孕Ⅱ号方。观察两组临床疗效 情况、血β-HCG 下降情况、异位妊娠包块变化情况、盆腔积血液吸收情况、腹痛消 失时间及药物副反应情况。结果：治疗组成功率为 86.67％、总有效率为 93.33％， 对照组成功率为 63.33％、总有效率为 63.33％，治疗组成功率及总有效率比对照组 高（P＜0.01），说明治疗组临床疗效优于对照组。血β-HCG 下降至正常所需时间比 较两组无明显差异性；腹痛消失时间比较、盆腔积血液吸收情况比较，治疗组比对照 组所用时间短，差异有显著性（P＜0.05）；药物副反应比较，两组副反应极小，发生 率均为 3.33％。结论：化瘀止血汤联合米非司酮保守治疗不稳定型异位妊娠是有效 治疗方案，其保守治疗成功率高而副反应小，有利于保留患者的输卵管。 关键词 中药；化瘀止血汤；米非司酮；不稳定型异位妊娠；中西医结合 The Clinical Study on Conservative Treatment of the Rupturing or Ruptured Ectopic Pregnancy with Hua-Yu-Zhi-Xue Decoction and Mifepristone(RU486) Specility: Gynecology of Traditional Chinese Medicine Author: Liu Li Tutor : Professor Wu Xinhua Abstract Objective: to study the therapeutic effect and the mechanism of ectopic pregnancy(EP) treated with Hua-Yu-Zhi-Xue Decoction and Mifepristone(RU486) in a conservation way. Methods: 60 cases EP were divided into two groups, the treatment group (30 cases) and the control group(30 cases). The treatment group were treated by Hua-Yu-Zhi-Xue Decoction and Mifepristone(RU486). The control group were treated by Gong-Wai-Yun- Ⅱ-Fang and RU486. Results: The total effective rate and the success ratio of the treatment group (93.33%,86.67%) is higher than that of the control group (63.33%,63.33%), with P＜0.01. The difference between two groups in the serum β -HCG normalizing time was not found. But the EP tumor’s volume decreased more greatly and the pelvic hematocele and bellyache disappeared more quickly in treatment group than in control group (P＜0.05). The medicine side effect of the two groups ar