原发性高血压患者血压变化规律及自主神经功能关系探析.docVIP

原发性高血压患者血压变化规律及自主神经功能关系探析【摘 要】 目的 了解高血压病患者血压变化规律与植物神经功能的关系。方法 选择高血压病患者（观察组）及血压正常者（对照组）各110例，同步进行24 h动态血压和动态心电图检查，对两组患者各参数进行对照分析。结果 ①观察组动态血压各参数均明显高于对照组（P＜0．05～0．001），SDNN、HF低于或显著低于对照组（P＜0．05～0．01），LF、LF/HF均高于对照组（P＜0．05）。②观察组夜间血压下降率减低（P＜0．05），其心率变异性指标中，除SDNN白昼较夜间增高外（P＜0．05），其他指标无明显差异。而对照组HRV各指标则与动态血压昼夜节律呈现出良好的相关性变化。结论 高血压病患者交感、迷走神经功能双重受损，表现为HRV减低和昼夜节律消失。提示临床在治疗上除积极降压外，还应考虑自主神经功能的受损情况，给予相应的处理。 【关键词】 高血压；植物神经功能；动态血压；心率变异性 Relationship of blood pressure variaty regulation and plant nerve function in patients with primury hypertension LI Xiao-zhu,CHEN En,FENG Pei-lan.The Ceatral People’s Hospital of Zhanjiang City,Zhanjiang 524037,China 【Abstract】 Objective To understand the relation ofblood pressure variety regulation and plant nerve function in patients with primary hypertension．Methods Choosing hypertension sufferers (observation set) and normal blood pressure(matched control), 110 cases for each，carrying on 24 hours dynamic state blood pressure and dynamic state electrocardiogram check synchronously，on checking against analysis to two sets of each parameter of sufferers．Results ①Each parameter of dynamil blood pressure in dservalion obviously higher than in the matched control (P＜0．05～0．001)，it reflected for 24 hours，various SDNN of frequency composition was high in the heart rate variation or obviously higher in matched control (P＜0．05～0．001)，mainly reflected the LF,LF/HF was higher than in the matched control(P＜0．05)， main reflection the HF of the pneumogastric nerves tension was low in the matched control (P＜0．05～0．001).②The nighttime blood pressure descend a rate to turn down (P＜0．05).In the heart rate variation index sign，in addition to comparing with nighttime，the SDNN daytime increased，other index signs had no obvious difference.But each index sign of HRVin matched control in dynamicblood pressure day and night,the regulation presented a good relativity variety．Conclusion The hypertension patient′s pneumogastric nerves function is dual damaged，expressi