米非司酮联合中药治疗子宫肌瘤疗效观察.docVIP

米非司酮联合中药治疗子宫肌瘤疗效观察[摘要] 目的 探讨米非司酮联合中药治疗子宫肌瘤的疗效。方法 入院确诊的70例子宫肌瘤患者随机分为治疗组（米非司酮+中药）和对照组（米非司酮）各35例，比较两组治疗的临床疗效及治疗前后血红蛋白、瘤体体积的变化。结果 两组间疗效比较，治疗组的疗效优于对照组（P＜0.01）。治疗后两组的血红蛋白均较治疗前明显升高，瘤体体积治疗后均较治疗前明显降低（P＜0.01）。两组血红蛋白及瘤体体积比较，治疗组的血红蛋白及瘤体体积较对照组改善更明显，差异有统计学意义（P＜0.05）。结论 米非司酮联合中药治疗子宫肌瘤可显著提高临床疗效，能够明显缩小瘤体体积，值得推广和应用。 [关键词]子宫肌瘤；米非司酮；中药；血红蛋白 [中图分类号] R711.74 [文献标识码] B [文章编号]1673-9701（2011）31-73-02 The Efficacy of Mifepristone Combined with Traditional Chinese Medicine in Treatment of Uterine Fibroids ZHOU Junhong1 WANG Hongyan2 1. Hubei Huangmei Orthopaedic Hospital (Apricot Medical School) ,Huangmei 435500, China; 2.Huangmei County People’s Hospital in Hubei Province, Huangmei 435500, China [Abstract] Objective To investigate the effects of mifepristone combined with traditional Chinese medicine in treatment of uterine fibroids. Methods Seventy cases were randomly divided into treatment group (mifepristone + medicine) and control group (mifepristone)with 35 cases in each in our hospital from February 2009 to February 2010，and the clinical efficacy and the changes of hemoglobin, tumor volume were comparde before and after treatment. Results The two groups were compared, the efficacy of treatment group was significantly higher than control group，and the difference was statistically significant（P＜0.01）. After treatment, the hemoglobin was significantly higher than that before treatment, tumor volume after treatment was significantly lower than that before treatment（P＜0.01） .Two groups hemoglobin and tumor volume was improved more significantly than the control group, the difference was statistically significant（P＜0.05）. Conclusion Mifepristone and traditional Chinese medicine treatment uterine fibroids can significantly improve the clinical efficacy and reduce the tumor size. It is should be promoted and applied. [Key words] Uterine fibroids; Mifepristone; Medicine ；Hemoglobin 子宫肌瘤是育龄期妇女的常见病、多发病，近年来，其发病率逐年升高，目前临床治疗子宫肌瘤的方法较多，且疗效报道不一[1]。随着社会进步及人们健康意识的提高，绝大多数子宫肌瘤患者均