脾氨肽辅助治疗小儿咳嗽变异性哮喘疗效观察.docVIP

脾氨肽辅助治疗小儿咳嗽变异性哮喘疗效观察【摘要】 目的：探讨脾氨钛辅助治疗小儿咳嗽变异性的临床疗效。方法：选取我院2008年9月~2010年10月收治的120例咳嗽变异性哮喘患者的临床资料，随机分为治疗组（60例）和对照组（60例），对照组患者采用抗感染、吸氧、激素、口服氨茶碱和白三烯受体拮抗剂（顺尔宁）等基础治疗，治疗组患者在基础治疗的基础上加用脾氨钛口服冻干液口服，每天睡觉前服1支，5d后，两日1支，连续治疗2个月，比较两组患儿咳嗽等临床症状改善情况和IgG水平改善情况。结果：用药2个月之后，治疗组患者显效41例，有效17例，无效2例，总有效率96.67%，对照组患者显效36例，有效15例，无效9例，总有效率85%，治疗组患者疗效优于对照组患者，两组患者疗效比较差异有统计学意义（p＜0.05）。两组患儿IgA水平差异有统计学意义（p＜0.05）。结论：对于咳嗽变异性哮喘患者在基础治疗的基础上脾氨钛口服冻干液， 可有效改善患者的临床症状，值得在临床推广。 【关键词】 咳嗽变异性哮喘；治疗方法；疗效观察；脾氨钛冻干液 Adjuvant treatment of splenic aminopeptidase cough variant asthma in children Efficacy Chen Ping (ARF Hospital of Jilin Province Siping City, Jilin Siping 136300) 【Abstract】Objective To investigate the adjuvant treatment of splenic ammonia titanium children with cough variant clinical efficacy. Methods in our hospital in September 2008~October 2010 admitted 120 patients with cough variant asthma clinical data of patients were randomly divided into treatment group (60 cases) and control group (60 cases), the control group were treated with anti-infection, oxygen, hormones, oral theophylline, and leukotriene receptor antagonists (Singulair) and so on the basis of the treatment group based on the treatment of patients based on the use of titanium oral freeze-dried liquid ammonia spleen orally every day before going to sleep Service 1, 5d, after two days one, continuous treatment of 2 months, patients were compared clinical symptoms such as cough and IgG levels to improve the situation. Results 2 months after the drug treatment group, 41 cases were markedly effective in 17 cases, 2 cases, total effective rate 96.67%, control group 36 cases were markedly effective in 15 cases, 9 cases, the total efficiency of 85%, treatment effective than the control group patients were two groups was statistically significant difference between the effect (P 1.4 统计学处理 应用SPSS13．0软件进行统计学处理，计数资料以％表示，计量资料以(x±s)表示，组内和组间比较分别采用t检验和x2检验。P 1