无锡市健康儿童及哮喘儿童睡眠障碍发生状况比较.docVIP

无锡市健康儿童及哮喘儿童睡眠障碍发生状况比较【摘要】 目的 了解无锡市3～12岁健康儿童和哮喘儿童睡眠呼吸障碍常见症状的发生率，比较哮喘儿童与健康儿童之间的差异。方法 抽取无锡市3个区3～12岁健康儿童2 354名和无锡市儿童医院哮喘门诊的3～12岁缓解期哮喘儿童300例，分别对其家长进行儿童睡眠状况问卷调查。结果 哮喘儿童睡眠障碍症状发生率为48.3%，其中睡眠频繁鼾症发生率为13.0%，喉头哽咽1.4%，张口呼吸?10.1%，睡眠呼吸暂停1.6%，磨牙0.6%，梦呓1.0%，梦游0.5%，睡眠中肢体抽动1.3%，睡眠不安18.1%。哮喘儿童睡眠障碍发生率较无呼吸道疾病的正常儿童高，其中睡眠频繁打鼾、睡眠不安、张口呼吸和睡眠呼吸暂停的发生率差异存在统计学意义。结论 哮喘儿童的睡眠障碍发生率高于无呼吸道疾病的正常儿童。 【关键词】 哮喘；睡眠障碍；对比研究；儿童 【中图分类号】 R 179 R 338.63 R 562.2?+5 【文献标识码】 A 【文章编号】 1000－9817(2007)05－0425－02 Comparison of Sleep Disorder Between Normal Children and Asthmatic Children in Wuxi/ CHEN Hao?jian, WEN Da?ke, XIE Juan?juan. Respiratory Disease Department of Wuxi Children’s Hospital, Wuxi(214002), Jiangsu Province, China 【Abstract】 Objective To study the incidence of sleep disorder among children aged 3-12 in Wuxi, and to compare the difference between healthy children and children with asthma. Methods 2 354 normal children and 300 asthmatic children were chosen in Wuxi, then a questionnaire survey was conducted among their parents. Results In asthmatic children, the incidence of sleep disorder was 48.3%. The incidence rates of frequent sleep snoring, choke gargling, mouth breathing, sleep apnea, molar teeth, night talking, somnambulance, limber apasm and sleep inquietude were 13.0%, 1.4%, ?10.1%, 1.6%, 0.6%, 1.0%, 0.5%, 1.3% and 18.1%.The prevalence rate of sleep disorder was higher among asthmatic children than the healthy ones. There were statistical significance in the difference of frequent sleep snoring, sleep inquiet, mouth breathing and sleep apnea between normal children and asthmatic children.Conclusion The prevalence rate of sleep disorder is higher among asthmatic children than the healthy children. 【Key words】 Asthma;Sleep disorders;Comparative study;Child 哮喘是一种慢性变态反应(过敏性气道炎症性疾病)，是由特应性体质及神经调节紊乱等内因与变应原及呼吸道病毒感染等外因相互作用，产生一系列免疫反应，在肥大细胞、嗜酸性粒细胞和T细胞等参与下，形成气道慢性炎症，由此引起气道高反应。国外研究资料显示，睡眠呼吸紊乱在哮喘患者中十分普遍[1]。为了解哮喘儿童中睡眠呼吸障碍常见症状的发生率，笔者于2003年6-10月，对无锡市3个区所属3所小学和幼儿园共2 354名儿童及无锡市儿童医院哮喘门诊300名缓解期哮喘儿