cardio-toxicity during chemotherapy feasibility of new diagnostic approaches化疗期间cardio-toxicity新的诊断方法的可行性.pdfVIP

Vol.2, No.4, 376-380 (2010) Health doi:10.4236/health.2010.24056 Cardio-Toxicity during chemotherapy: feasibility of new diagnostic approaches 1 2 1 1 2 Fable Zustovich , Mario Trivellato , Renato Ceravolo , Davide Pastorelli , Rosanna Canton , Lorena Buratin2 3 3 1 3 , Monica Mion , Martina Zaninotto , Martina Mattiazzi , Mario Plebani , Giuseppe Cartei1 1Oncologia Medica 1° piano, IOV – IRCCS, Padova, Italy; fable.zustovich@ioveneto.it 2Servizio di Cardiologia ULSS16 c/o IRA, Padova, Italy 3Dipartimento di Medicina di Laboratorio, Università – Azienda Ospedaliera, Padova, Italy Received 25 October 2009; revised 28 November 2009; accepted 5 December 2009. ABSTRACT The evaluation of the cardiac safety during cardio toxic chemotherapy is usually based on standard EKG, Chemotherapy induced cardio-toxicity is a well EKG Holter and mostly using echo-color doppler car- known side effect of anticancer treatments, diography. All these methods reveal cardiac damage moreover the 70% of all tumors involve patients when macroscopic morphological alterations have been over 65 years-old, frequently with cardiac co- reached, thus when damage is already present and often morbidity. We evaluated the feasibility of the irreversible. application during chemotherap