risk factors for radiographic tibiofemoral knee osteoarthritis the wuchuan osteoarthritis study射线照相胫股的膝骨关节炎吴川骨关节炎的危险因素研究.pdfVIP

Hindawi Publishing Corporation International Journal of Rheumatology Volume 2010, Article ID 385826, 6 pages doi:10.1155/2010/385826 Research Article Risk Factors for Radiographic Tibiofemoral Knee Osteoarthritis: The Wuchuan Osteoarthritis Study Jianhao Lin,1 Rujun Li,1 Xiaozheng Kang,2 and Hu Li1 1Arthritis Institute, Peking University, People’s Hospital, Beijing 100044, China 2 Department of Thoracic Surgery, Beijing Cancer Hospital and Institute, Beijing 100142, China Correspondence should be addressed to Jianhao Lin, jianhao lin@ Received 29 October 2010; Accepted 26 November 2010 Academic Editor: Jean-Pierre Pelletier Copyright © 2010 Jianhao Lin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Objective. To investigate the risk factors of radiographic tibiafemoral knee osteoarthritis (OA). Methods. A population-based cross- sectional survey was conducted in Wuchuan County. A questionnaire and bilateral weight-bearing posterior-anterior semi-flexed knee radiographs were completed and read for Kellgren and Lawrence (K/L) grade and joint space narrowing (JSN; 0–3 scale) in each compartment. An logistic regression analysis was performed for radiographic tibiafemoral, lateral compartment, and medial compartment knee OA, respectively. Adjusted odds ratios (OR) and 95% confidence intervals (CI) were calculated. Results. Age, sex, and knee injury were strongly associated with tibiafemoral, lateral and medial compartment knee OA. BMI also had a dose- response relationship with them. Physical activity level, and physical activity exposure at work, not significantly though, were associated with an elevated