spontaneous object recognition in the g？ttingen minipig自发的对象识别g 业务minipig.pdfVIP

NEURAL PLASTICITY VOLUME NO. 2002 9, 4, Spontaneous Object Recognition in the Giittingen Minipig Anette Moustgaard 1,2, Nanna Marie Lind ’, Ralf Hemmingsen and Axel Kornerup Hansen 1Department ofPsychiatry, H:SBispebjerg, University Hospital ofCopenhagen, Bispebjerg Bakke 23, DK-2400 Copenhagen NV, Denmark, ZDivision ofLaboratoryAnimal Science and Welfare, Department ofPharmacology andPathobiology, The Royal Veterinary and Agricultural University, Biilowsvej 17, DK- 1870 Frederiksberg C, Denmark ABSTRACT known examples are the delayed matching or non- matching to sample tasks that were initially G/ittingen minipigs were tested in an object developed for monkeys (see for instance Mishkin recognition procedure based on spontaneous Delacour, 1975). The memory for many kinds of exploration. Eight pigs were exposed to two stimuli can be tested in such paradigms, but similar objects in a sample trial and after a one- typically spatial positions or visual stimuli, hour delay exposed to two objects, one familiar including objects, have been used. There has, and one novel, in a test trial. The pigs explored however, for many years been a lack of animal the novel object significantly more than the tasks that measure spontaneous trial-unique familiar object in the test trial (p0.05), thereby memory. This has especially been a problem in showing recognition of the familiar object.