hydrochloric acid penehyclidine clinical studies for the treatment of acute organophosphorus pesticide poisoning（盐酸penehyclidine临床研究治疗急性有机磷农药中毒）.docVIP

Hydrochloric acid penehyclidine clinical studies for the treatment of acute organophosphorus pesticide poisoning [Abstract] Objective: the observation hydrochloric penehyclidine (rescue of acute organophosphorus pesticide poisoning patients in clinical efficacy. Methods: Penehyclidine hospital for emergency treatment of 47 cases of acute organophosphorus pesticide poisoning patients as the observation group, giving hydrochloric of penehyclidine Joint pralidoxime chloride treatment and the past traditional undergraduate application atropine chlorination pralidoxime for emergency treatment of 47 patients with acute organophosphate poisoning patients as a control group, the two groups were compared clinical efficacy. Results: The clinical efficacy, the average length of stay, CHE recovery time, poisoning symptoms disappear time and conscious comparison with the control group, the difference had statistical significance (P lt;0.05, comparable. 1.2 Treatment Immediately after the admission of the two groups were given thorough gastric lavage or remove pesticide residues on the surface of the skin and clothing, the routine given early cholinesterase can be agents of pralidoxime chloride, to give catharsis, rehydration, oxygen, etc., and tight monitor the patient’s vital signs. attention to gastric lavage gastric washing optional: trichlorfon 1:5000 potassium permanganate gastric lavage, internal phosphorus uptake, parathion 2% sodium bicarbonate gastric lavage unknown pesticides gastric lavage with 32 ~ 36 ℃ warm water. observation group was treated with the amyl acetate hydrochloride Kui ether injection (Penehyclidine Pharmaceutical Co., Ltd., Chengdu force Fest production, batch number: 060,903 and 071,003, specifications: Each 1 mg, according to degrees of poisoning in patients treated with different doses of poisoning patients after rescuing the basic cure, such as withdrawalgt; 12 h without obvious symptoms of poisoning, and whole blood cholinesterase activ